Assessment of the antibacterial activity of phenylethanoid glycosides from Phlomis lanceolata against multiple-drug-resistant strains of Staphylococcus aureus.

Journal of Natural Medicines
Hossein NazemiyehSatyajit D Sarker

Abstract

Three phenylethanoid glycosides, forsythoside B (1), phlinoside C (2) and verbascoside (3), were isolated from the methanol extract of the leaves of Phlomis lanceolata, an Iranian medicinal plant, by reversed-phase preparative high-performance liquid chromatography (HPLC), and the structures of these compounds were elucidated conclusively by ultraviolet (UV), mass spectrometry (MS) and a series of 1D and 2D nuclear magnetic resonance (NMR) analyses. The antibacterial properties of 1-3 against five multi-drug-resistant (MDR) strains of Staphylococcus aureus have been assessed by the rapid and robust microtitre-plate-based serial dilution method. While compounds 1 and 3 showed considerable activities against all five strains, compound 2 was inactive at the test concentrations.

Citations

Aug 3, 2016·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Zhenzhen Xue, Bin Yang
Dec 5, 2009·Phytomedicine : International Journal of Phytotherapy and Phytopharmacology·W-L Jiang Jian-Hou
May 20, 2008·Journal of Natural Medicines·Abbas DelazarSatyajit Dey Sarker
Oct 15, 2009·Phytotherapy Research : PTR·Miao YeJin-Feng Hu
Dec 29, 2009·Journal of Natural Medicines·Hossein NazemiyehSatyajit Dey Sarker
Apr 28, 2010·Plant Foods for Human Nutrition·Víctor LópezMaria Isabel Calvo
Jun 20, 2018·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Izabela Grzegorczyk-Karolak, Anna K Kiss
Aug 12, 2020·Medicinal Research Reviews·Lipeng WuBaiyi Lu
Dec 8, 2011·Phytotherapy Research : PTR·Wang-Lin Jiang Jian-Hou
Feb 9, 2012·European Journal of Drug Metabolism and Pharmacokinetics·Yang ChuYonghong Zhu
Jul 1, 2009·Journal of Ethnopharmacology·Ilef Limem-Ben AmorLeila Chekir-Ghedira

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antifungals

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Antifungals (ASM)

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.