Assessment of the concentrations of various advanced glycation end-products in beverages and foods that are commonly consumed in Japan

PloS One
M TakeuchiS Yamagishi

Abstract

Dietary consumption has recently been identified as a major environmental source of pro-inflammatory advanced glycation end-products (AGEs) in humans. It is disputed whether dietary AGEs represent a risk to human health. Nε-(carboxymethyl)lysine (CML), a representative AGE compound found in food, has been suggested to make a significant contribution to circulating CML levels. However, recent studies have found that the dietary intake of AGEs is not associated with plasma CML concentrations. We have shown that the serum levels of glyceraldehyde-derived AGEs (Glycer-AGEs), but not hemoglobin A1c, glucose-derived AGEs (Glu-AGEs), or CML, could be used as biomarkers for predicting the progression of atherosclerosis and future cardiovascular events. We also detected the production/accumulation of Glycer-AGEs in normal rats administered Glu-AGE-rich beverages. Therefore, we assessed the concentrations of various AGEs in a total of 1,650 beverages and foods that are commonly consumed in Japan. The concentrations of four kinds of AGEs (Glu-AGEs, fructose-derived AGEs (Fru-AGEs), CML, and Glycer-AGEs) were measured with competitive enzyme-linked immunosorbent assays involving immunoaffinity-purified specific antibodies. The results of t...Continue Reading

References

Dec 15, 1992·Proceedings of the National Academy of Sciences of the United States of America·H VlassaraR Bucala
Jan 1, 1992·Advances in Pharmacology·R Bucala, A Cerami
Jan 1, 1995·Annual Review of Medicine·M Brownlee
Jun 10, 1997·Proceedings of the National Academy of Sciences of the United States of America·T KoschinskyH Vlassara
Jul 7, 2001·Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Métabolisme·M EndoT Koike
Jul 29, 2004·Journal of the American Dietetic Association·Teresia GoldbergHelen Vlassara
Aug 4, 2004·Medical Hypotheses·M Takeuchi, S Yamagishi
Sep 3, 2004·Diabetes/metabolism Research and Reviews·Casper G SchalkwijkVictor W M van Hinsbergh
Apr 25, 2007·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Jaime UribarriHelen Vlassara
Sep 15, 2007·Molecular Nutrition & Food Research·Katarína Sebeková, Veronika Somoza
Dec 17, 2008·European Journal of Nutrition·Takashi SatoMasayoshi Takeuchi
Apr 24, 2009·Journal of Alzheimer's Disease : JAD·Masayoshi Takeuchi, Sho-ichi Yamagishi
Mar 10, 2010·Laboratory Investigation; a Journal of Technical Methods and Pathology·Masayoshi TakeuchiSho-ichi Yamagishi
May 26, 2010·Journal of the American Dietetic Association·Jaime UribarriHelen Vlassara
May 26, 2011·Nature Reviews. Endocrinology·Helen Vlassara, Gary E Striker
Jul 23, 2013·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Malene W PoulsenLars O Dragsted

❮ Previous
Next ❯

Citations

Mar 5, 2016·International Journal of Cardiology·Dorien DeluykerVirginie Bito
Jun 21, 2017·Nutrients·Masayoshi TakeuchiMikihiro Tsutsumi
May 15, 2019·Clinical and Translational Gastroenterology·Dana Ivancovsky-WajcmanRevital Kariv
Aug 4, 2019·Diabetes & Vascular Disease Research : Official Journal of the International Society of Diabetes and Vascular Disease·Ami SotokawauchiSho-Ichi Yamagishi
Nov 26, 2019·Critical Reviews in Food Science and Nutrition·Zhili LiangZhao Yang
Jul 28, 2020·The British Journal of Nutrition·Parivash GhorbaninejadSakineh Shab-Bidar
Apr 17, 2020·Food Science and Biotechnology·Ho-Young ParkYoonsook Kim
Oct 3, 2018·Aging and Disease·Maxime FournetAlexis Desmoulière
May 31, 2019·BMJ : British Medical Journal·Bernard SrourMathilde Touvier
Apr 8, 2020·Oxidative Medicine and Cellular Longevity·Anna PerroneFederico Martinelli
Oct 22, 2020·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Elom K AglagoMazda Jenab
Dec 29, 2020·Critical Reviews in Food Science and Nutrition·Chenzhipeng NieLi Wang
Dec 19, 2020·Comprehensive Reviews in Food Science and Food Safety·Qiaozhi ZhangLinglin Fu
Jun 2, 2021·European Journal of Clinical Investigation·Luís F GriloSusana P Pereira
Oct 28, 2021·Journal of Agricultural and Food Chemistry·Agustin Martin-MoralesKenji Sato
Sep 30, 2021·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Omonefe O OmofumaSusan E Steck
Dec 30, 2021·ACS Applied Materials & Interfaces·Gopal AmmanathBo Liedberg

❮ Previous
Next ❯

Methods Mentioned

BETA
protein assay
AGE-RSA
affinity purification
enzyme-linked immunosorbent assay
ELISA

Related Concepts

Related Feeds

Cardiovascular Disease Pathophysiology

Cardiovascular disease involves several different processes that contribute to the pathological mechanism, including hyperglycemia, inflammation, atherosclerosis, hypertension and more. Vasculature stability plays a critical role in the development of the disease. Discover the latest research on cardiovascular disease pathophysiology here.

Biomarkers for Cardiovascular Risk Assessment

Sensitive and accurate biomarkers used in cardiovascular risk prediction can potentially be used to manage the risk of cardiovascular disease. Discover the latest research on Biomarkers for Cardiovascular Risk Assessment here. Discover the latest research on Biomarkers for Cardiovascular Risk Assessment here.

Atherosclerosis Disease Progression

Atherosclerosis is the buildup of plaque on artery walls, causing stenosis which can eventually lead to clinically apparent cardiovascular disease. Find the latest research on atherosclerosis disease progression here.

Related Papers

Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology
Noel T MuellerMark A Pereira
Nihon eiseigaku zasshi. Japanese journal of hygiene
Yuriko KikuchiSatoshi Sasaki
© 2022 Meta ULC. All rights reserved