Assessment of the efficacy and safety of platelet poor plasma gel as autologous dermal filler for facial rejuvenation

Journal of Cosmetic Dermatology
Noha Nabil DoghaimYomna Mazid El-Hamd Neinaa

Abstract

The popularity of dermal fillers has grown rapidly in the last few years for facial rejuvenation. Plasma gel is an autologous gelatinous material that is prepared from the patient's own platelet poor plasma. To evaluate the clinical efficacy and safety of plasma gel injection as a dermal filler for facial rejuvenation. The current study was carried out on 52 females presented with facial aging divided into two groups: Group A included 34 females with facial wrinkles, and Group B included 18 females with tear trough deformity. After taking written informed consent, they received two sessions of plasma gel injections at 2-week interval and followed up monthly for 3 months. They were assessed clinically before treatment sessions and at the end of follow-up period. Both studied groups showed immediate significant clinical improvement after plasma gel injection that maintained till the end of follow-up period. This finding was confirmed by significant reduction in the mean values of Wrinkle Severity Rating Scale (WSRS) in Group A and Tear Trough Rating Scale (TTRS) in group B, and significant improvement of skin homogeneity and texture in both groups. In general, the reported side effects were minimal and transient. Autologous plate...Continue Reading

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Citations

Aug 1, 2020·Chinese Medical Journal·Chun-Hu WangFa-Cheng Li
Feb 1, 2020·Journal of Cutaneous and Aesthetic Surgery·Yasemin Oram, Gursel Turgut
Nov 20, 2020·Journal of Cutaneous and Aesthetic Surgery·Sumit GuptaCharisma Kannan
Jul 14, 2021·Journal of Cosmetic Dermatology·Motaz DairiEman Aldigs
Jan 4, 2022·Journal of Cosmetic and Laser Therapy : Official Publication of the European Society for Laser Dermatology·Yasemin OramGürsel Turgut
Jun 23, 2021·Photodermatology, Photoimmunology & Photomedicine·May Moustafa MohamedRehab Mohammed Salem

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