PMID: 3762126Aug 1, 1986Paper

Assessment of the fluorescein dye test for prediction of skin flap viability in pigs

The Journal of Surgical Research
C Y PangG H Sasaki

Abstract

The visual fluorescein dye test for prediction of actual skin flap viability was evaluated in pigs. Two delayed random (4 X 10 cm) and arterial (4 X 20 cm) skin flaps were constructed on one flank of a pig, and four mirror-image skin flaps were raised acutely on the other flank of the same pig. Sodium fluorescein dye (15 mg/kg) was injected intravenously 1 and 18 hr after raising of flaps. The maximum length and area of dye stain in these flaps (N = 24) were assessed under Wood's lamp illumination, 15 min after dye injection. The actual maximum lengths and areas of skin survival of these flaps in the same pig were measured 7 days postoperatively. It was observed that visual fluorescein dye test performed 1 hr after surgery significantly (P less than 0.05) underestimated the maximum length and area of actual skin survival. On the other hand, when the fluorescein dye test was performed 18 hr postoperatively, the maximum length of dye stain and the maximum length of actual skin viability were highly correlated (r = 0.97, N = 24, P less than 0.01). Their mean values were similar (10.6 +/- 0.8 vs 10.8 +/- 0.7 cm, mean +/- SEM), and their mean coefficient of variation was 5.6 +/- 1.6%. Similarly, there was a high degree of correlatio...Continue Reading

References

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Citations

Oct 31, 2002·Microsurgery·Shigeru IchiokaKiyonori Harii
Nov 1, 1991·British Journal of Plastic Surgery·T TakatoC B Turley
May 1, 1992·British Journal of Plastic Surgery·G I Taylor, J H Palmer
Jul 1, 1995·British Journal of Plastic Surgery·M L KreidsteinC Y Pang
Jan 12, 2002·Plastic and Reconstructive Surgery·Kayvan T Khiabani, Carolyn L Kerrigan
Jun 28, 2002·Plastic and Reconstructive Surgery·Kayvan T Khiabani, Carolyn L Kerrigan
Feb 1, 1992·The Journal of Surgical Research·A ZhongC R Forrest
Sep 23, 1997·Scandinavian Journal of Plastic and Reconstructive Surgery and Hand Surgery·L Birk-SørensenV E Hjortdal
Dec 2, 2005·Scandinavian Journal of Plastic and Reconstructive Surgery and Hand Surgery·Zekeriya TosunNedim Savaci
Mar 1, 1990·The Journal of Surgical Research·C R ForrestP C Neligan

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