Assessment of the interface between retroperitoneal fat infiltration of pancreatic ductal carcinoma and the major artery by multidetector-row computed tomography: surgical outcomes and correlation with histopathological extension.

World Journal of Surgery
Yusuke YamamotoNobuyoshi Hiraoka

Abstract

Precise assessment of retroperitoneal invasion is clinically important to allow the achievement of negative margin resections. The clinical records of 132 patients who underwent macroscopic curative pancreaticoduodenectomy for invasive ductal carcinoma of the pancreas between 2004 and 2008 were retrospectively examined. The clinicopathological factors, including retroperitoneal fat infiltration classified into four groups by multidetector-row computed tomography (MDCT), were analyzed. The relationship between the grade of retroperitoneal fat infiltration and surgical outcomes, as well as various histopathological factors, was also investigated. The 5 year survival rate was 55.6 % for grade 0 infiltration (n = 8), 38.7 % for grade 1 (n = 54), 16.4 % for grade 2 (n = 49), and 0 % for grade 3 (n = 21). There were significant differences in survival in each group. Extrapancreatic nerve invasion and the surgical margin status were significantly associated with retroperitoneal fat infiltration demonstrated on MDCT. According to the grading classification among the 43 patients with pathological portal vein invasion, the 5 year survival rate was 45.9 % for patients with grade 1, which was significantly better survival that those with g...Continue Reading

References

May 1, 1996·Abdominal Imaging·E M LoyerC Charnsangavej
Mar 22, 2002·AJR. American Journal of Roentgenology·Carlos VallsRosa Jorba
Apr 16, 2004·Pancreas·Seiki MatsunoKazunori Takeda
Mar 18, 2005·Journal of Computer Assisted Tomography·Hui LiWen Hui Lou
Jul 26, 2006·Annals of Surgical Oncology·Gauri R VaradhacharyRobert A Wolff
Nov 23, 2006·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Jordan M WinterCharles J Yeo
Nov 23, 2006·AJR. American Journal of Roentgenology·Tomoaki IchikawaTsutomu Araki
Dec 7, 2007·The American Journal of Surgical Pathology·Shuichi MitsunagaAtsushi Ochiai
May 13, 2008·Journal of the American College of Surgeons·Matthew H G KatzRosa F Hwang
Jan 13, 2009·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Sascha A MüllerMarkus W Büchler
Sep 1, 2009·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·Caroline S Verbeke, Krishna V Menon

❮ Previous
Next ❯

Citations

Oct 8, 2014·Pancreatology : Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]·Yusuke YamamotoEigo Otsuji
Jun 4, 2014·Journal of Hepato-biliary-pancreatic Sciences·Mehdi OuaïssiJean-Yves Mabrut

❮ Previous
Next ❯

Related Concepts

Related Feeds

Breast Invasive Carcinoma

Invasive breast cancers indicate a spread into breast tissues and lymph nodes. Here are the latest discoveries pertaining to breast invasive carcinomas.

Breast Invasive Carcinoma (Keystone)

Invasive breast cancers indicate a spread into breast tissues and lymph nodes. Here are the latest discoveries pertaining to breast invasive carcinomas.

Carcinoma, Ductal

Ductal carcinoma is a malignant neoplasm involving the ductal systems of any of a number of organs, such as the mammary glands, pancreas, prostate or lacrimal gland. Discover the latest research on ductal carcinoma here.