Assessment of the minimum clinically important difference in neurological function and quality of life after surgery in cervical spondylotic myelopathy patients: a prospective cohort study

European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
Feifei ZhouZhongjun Liu

Abstract

The purpose of this study was to evaluate the application of the minimum clinically important difference (MCID) concept to postoperative clinical results by using a prospective cohort study in Chinese patients with cervical spondylotic myelopathy (CSM). The sample consisted of 113 patients who underwent surgical treatment for CSM in our hospital between February 2008 and November 2012. The preoperative and 1-year postoperative modified Japanese Orthopaedic Association (mJOA) scores, mJOA score recovery rate, physical component summary (PCS) and mental component summary (MCS) of the Short Form 36 were collected. The MCID of each outcome measurement was calculated by four approaches including average change, minimum detectable change, change difference and receiver operating characteristic curve. The responsiveness of each measurement was then analyzed. The patients presented a statistically significant improvement (p < 0.01) postoperatively in mJOA, PCS, and MCS. The MCID calculated by four approaches varied from 4.09 to 9.62 for the PCS, 3.11 to 7.41 for the MCS, 1.25 to 3.07 for mJOA score, and 31.37 to 44.02% for mJOA recovery rate. In addition, the improvement of the mJOA score owned the highest responsiveness of the four ou...Continue Reading

References

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Citations

Mar 10, 2016·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Shujie WangXisheng Weng
Mar 31, 2017·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Vanessa L KronzerMichael S Avidan
Jun 29, 2017·Spine·María J Díaz-ArribasOscar S Martín-Pariente
Jul 19, 2019·The Journal of Bone and Joint Surgery. American Volume·Anne E H BroekemaRemko Soer
Jan 25, 2020·Nature Reviews. Neurology·Jetan H BadhiwalaMichael G Fehlings
Jan 5, 2017·Clinical Orthopaedics and Related Research·Mitchell Maltenfort, Claudio Díaz-Ledezma
Mar 17, 2019·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·So KatoKatsushi Takeshita
Nov 24, 2020·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Masaaki MachinoShiro Imagama
Nov 19, 2021·British Journal of Neurosurgery·Yuri HirayamaMark R N Kotter

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