PMID: 15077681Apr 14, 2004Paper

Assessment of the relationship of bispectral index values, hemodynamic changes, and recovery times associated with sevoflurane or propofol anesthesia in pigs

American Journal of Veterinary Research
M F Martín-CanchoJ Usón-Gargallo

Abstract

To evaluate bispectral index (BIS) values in pigs during anesthesia maintained with sevoflurane-fentanyl or propofol-fentanyl as a predictor of changes in hemodynamic parameters and duration of recovery from anesthesia. 12 pigs. Pigs were randomly allocated to undergo 1 of 2 anesthetic regimens. Anesthesia was induced with propofol (2 mg/kg, i.v.); 6 pigs were administered sevoflurane via inhalation (1 minimum alveolar concentration [MAC] at a fresh gas flow rate of 3 L/min; group I), and 6 were administered propofol (11 mg/kg/h, i.v.; group II). All pigs received fentanyl (2.5 mg/kg, i.v., q 30 min). After abdominal surgery, pigs were allowed to recover from anesthesia. Cardiovascular variables and BIS values were recorded at intervals throughout the procedure; duration of recovery from anesthesia was noted. No correlation was established between arterial blood pressure and BIS and between heart rate and BIS. Mean BIS at discontinuation of administration of the anesthetic agent was greater in group-II pigs (65.2 +/- 10.6 minutes) than in group-I pigs (55.8 +/- 2.9 minutes). However, recovery from anesthesia was significantly longer in group II (59.80 +/- 2.52 minutes) than in group I (9.80 +/- 2.35 minutes). In swine anestheti...Continue Reading

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Citations

May 22, 2009·British Journal of Anaesthesia·M ZaballosM J Anadón
Aug 23, 2005·American Journal of Veterinary Research·Joanna C MurrellLudo J Hellebrekers
Jul 7, 2009·Annales Françaises D'anesthèsie Et De Rèanimation·L BeydonM Gogny
Mar 5, 2016·British Journal of Anaesthesia·A G Bradbury, R E Clutton
Dec 2, 2015·Veterinary Anaesthesia and Analgesia·Rocio NavarreteJuan Morgaz
Feb 22, 2012·Transplant International : Official Journal of the European Society for Organ Transplantation·Philipp StieglerKarlheinz Tscheliessnigg
Aug 13, 2011·Veterinary Anaesthesia and Analgesia·Flavia RestituttiOuti M Vainio
Dec 5, 2009·The Journal of Veterinary Medical Science·Kazuto YAMASHITAWilliam W MUIR
Apr 21, 2012·Laboratory Animals·Aura Silva, Luis Antunes
Apr 19, 2019·Circulation. Heart Failure·Petra NiederbergerSarah L Longnus

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