Assessment of the role of LASER-Doppler in the treatment of port-wine stains in infants

Journal of Pediatric Surgery
Tessa MermodAnthony de Buys Roessingh

Abstract

Port-wine stains (PWS) are malformations of capillaries in 0.3% of newborn children. The treatment of choice is by pulsed dye LASER (PDL), and requires several sessions. The efficacy of this treatment is at present evaluated on the basis of clinical inspection and of digital photographs taken throughout the treatment. LASER-Doppler imaging (LDI) is a noninvasive method of imaging the perfusion of the tissues by the microcirculatory system (capillaries). The aim of this paper is to demonstrate that LDI allows a quantitative, numerical evaluation of the efficacy of the PDL treatment of PWS. The PDL sessions were organized according to the usual scheme, every other month, from September 1, 2012, to September 30, 2013. LDI imaging was performed at the start and at the conclusion of the PDL treatment, and simultaneously on healthy skin in order to obtain reference values. The results evidenced by LDI were analyzed according to the "Wilcoxon signed-rank" test before and after each session, and in the intervals between the three PDL treatment sessions. Our prospective study is based on 20 new children. On average, the vascularization of the PWS was reduced by 56% after three laser sessions. Compared with healthy skin, initial vascular...Continue Reading

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Citations

Oct 28, 2016·Microcirculation : the Official Journal of the Microcirculatory Society, Inc·Gregory BarshteinSaul Yedgar
Apr 1, 2021·Journal of Cosmetic Dermatology·Jeta BuchMohamad Goldust

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