Assessment of transthyretin combined with mini nutritional assessment on admission provides useful prognostic information in patients with acute decompensated heart failure

International Heart Journal
Norio SuzukiYoshihiro J Akashi

Abstract

Decreased Transthyretin (TTR) can be observed in heart failure patients with malnutrition evaluated by the Mini Nutritional Assessment (MNA). This study investigated whether a combination of different nutritional assessment methods would be useful for assessing prognosis in patients with acute decompensated heart failure (ADHF).This prospective study included 52 patients with ADHF (mean age, 71.1 ± 14.7 years; men 55.8%) who were admitted to our hospital between June 2012 and August 2013. On admission, nutritional status was evaluated according to levels of TTR and the MNA. Of 52 patients, 28 (53.8%) had TTR < 15 mg/dL, 39 (75.0%) had malnutrition or were at risk of malnutrition (MNA score ≤ 23.5), and 21 (40.4%) were categorized into group L (MNA score ≤ 23.5 and TTR < 15 mg/dL). Readmission due to worsening heart failure occurred in 12 patients (23.1%), and there were 4 (7.7%) allcause deaths. The 1-year event-free survival rates in group L and the remaining patients (group O) were 27.7% and 85.6%, respectively (P = 0.001). Using Cox multivariate analysis, group L also had a poorer prognosis (hazard ratio 4.35, 95% confidence interval 1.26-17.74, P = 0.020).MNA revealed that 75% of patients with ADHF had malnutrition or were ...Continue Reading

References

Mar 1, 1996·Age and Ageing·D KingM Lye
Feb 18, 2003·Current Opinion in Clinical Nutrition and Metabolic Care·Comasia A RagusoClaude Pichard
Jul 29, 2004·Journal of the American Dietetic Association·M Patricia FuhrmanCharles M Mueller
Oct 8, 2005·The American Journal of Clinical Nutrition·Olivier BouillanneChristian Aussel
Oct 8, 2005·The American Journal of Clinical Nutrition·Nadya KaganskyShmuel Levy
Dec 8, 2005·Current Heart Failure Reports·Yoshihiro J AkashiStefan D Anker
Jul 25, 2006·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Sachiko IzawaAkihisa Iguchi
Mar 27, 2007·Circulation Journal : Official Journal of the Japanese Circulation Society·Muneyoshi OgawaUNKNOWN Northern Iwate Heart Disease Registry Consortium
Jul 29, 2008·Clinical Biochemistry·Arun DevakondaLarry H Bernstein
Aug 1, 2009·Circulation Journal : Official Journal of the Japanese Circulation Society·Miyuki Tsuchihashi-MakayaUNKNOWN JCARE-CARD Investigators
Jun 3, 2011·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Ioannis GioulbasanisVassilis Georgoulias
Jun 10, 2011·Revista española de cardiología·Juan L Bonilla-PalomasJosé Suárez de Lezo
Aug 16, 2012·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Masaru HorioUNKNOWN Collaborators Developing the Japanese Equation for Estimated GFR
Oct 6, 2012·International Heart Journal·Taira FukudaToshiaki Nakajima
Oct 12, 2012·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Ashim AggarwalGeetha Bhat
Oct 20, 2012·International Journal of Cardiology·Patrícia LourençoPaulo Bettencourt
Nov 28, 2012·Circulation Journal : Official Journal of the Japanese Circulation Society·Yoshiharu KinugasaKazuhiro Yamamoto
Jul 3, 2013·Circulation Journal : Official Journal of the Japanese Circulation Society·Kotaro NochiokaUNKNOWN CHART-2 Investigators
Aug 9, 2013·International Heart Journal·Naoko KatoRyozo Nagai
Feb 4, 2014·Journal of Cardiac Failure·Juan Luis Bonilla-PalomasAntonia Villar-Ráez

❮ Previous
Next ❯

Citations

Dec 26, 2015·Journal of the Academy of Nutrition and Dietetics·Ryoko SomeyaKazuo Kimura
Aug 30, 2018·Nutrition & Dietetics : the Journal of the Dietitians Association of Australia·Haruyo MatsuoYuichi Maeno
Apr 10, 2018·Circulation Journal : Official Journal of the Japanese Circulation Society·Satoshi KatanoTetsuji Miura
Jan 31, 2019·The Journal of Nutrition, Health & Aging·H WakabayashiR Momosaki
Jul 14, 2020·Circulation Journal : Official Journal of the Japanese Circulation Society·Kazuhiro YamamotoUNKNOWN Japanese Heart Failure Society, Expert Consensus Writing Committee

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.