PMID: 9525753Apr 3, 1998Paper

Assessment of vascularity in reactive lymph nodes by means of D-galactose contrast-enhanced Doppler sonography

Investigative Radiology
C WillamR Felix

Abstract

A prospective study in signal-enhanced Doppler sonography of lymph nodes that were assumed pretherapeutically to be benign was performed to investigate characteristic sonomorphologic features and vascularity of reactively enlarged lymph nodes. Thirty-four patients with enlarged superficial lymph nodes of the neck were examined first by B-scan sonography then by Doppler sonography before and after administration of an ultrasound signal-enhancing agent. In B-scan sonography, lymph nodes were classified into three groups according to their sonomorphologic features: (1) homogeneous parenchyma, (2) a centrally located echogenoic line, and (3) a echogenoic "hilus reflex." In conventional and contrast-enhanced Doppler sonography, peak flow rate, pulsatility index, and resistive index were assessed. Sonomorphologic criteria were compared with histologic findings. Reactively enlarged lymph nodes showed characteristic sonomorphologic patterns correlating to their histologic features. Echogenicity of the hilus corresponded to fibrosis (centrally located echogenoic line in 13 nodes; 38.2%) or fatty involution of the hili (echogenoic hilus reflex in 15 nodes; 44.1%). Administration of the galactose-based ultrasound contrast enhancer facilit...Continue Reading

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Citations

May 5, 2006·Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete·B M StoeckelhuberC U Bergmann-Koester
May 3, 2003·Clinical Radiology·A Ahuja, M Ying
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Feb 9, 2006·European Journal of Radiology·Patrick Wunderbaldinger
Dec 10, 1999·Investigative Radiology·V M Runge
Sep 24, 2005·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Pedro Weslley Souza RosárioAlvaro Luís Barroso

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