PMID: 6975804Aug 1, 1981Paper

Associated particle aggregates in juxtaparanodal axolemma and adaxonal Schwann cell membrane of rat peripheral nerve

Journal of Neurocytology
C StolinskiG Gabriel

Abstract

Freeze-fracture observations have been made on unfixed cryoprotected, and glutaraldehyde-perfused and cryoprotected rat sciatic nerve. In the juxtaparanodal region of the internode, numerous particle clusters were observed on the axolemmal E face and rings of particles of uniform size on the P face of the adaxonal Schwann cell membrane. Both of these particle aggregates were concentrated in the internodal region immediately adjacent to the paranode (juxtaparanodal). The findings provide evidence for a close association between the two particle formations, suggesting a unitary structure forming links between the axolemma and Schwann cell membrane. Figures are given for the density distribution of these particles at the juxtaparanodal region. They were rarely observed on membrane fracture faces of the general internodal regions. It is possible that these particle formations may represent potassium channels or that they could provide channels for other metabolic communication between the Schwann cell and the axon.

References

Jan 1, 1977·Journal of the Neurological Sciences·D C Quick, S G Waxman
Jan 1, 1977·Proceedings of the National Academy of Sciences of the United States of America·J M Ritchie, R B Rogart
Jul 1, 1979·The Journal of Physiology·S Y ChiuD Stagg
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Citations

Aug 13, 1984·Brain Research·J H Tao-Cheng, J Rosenbluth
Nov 1, 1982·Journal of the Neurological Sciences·C Stolinski, A S Breathnach
Jan 1, 1987·Journal of the Neurological Sciences·S G Waxman, J A Black
Feb 1, 2011·Brain : a Journal of Neurology·Arthur K AsburyAlastair Compston
Dec 10, 1999·Annals of the New York Academy of Sciences·S S Scherer
Apr 10, 2002·Journal of the Peripheral Nervous System : JPNS·Steven S Scherer, Edgardo J Arroyo
Dec 20, 2003·Nature Reviews. Neuroscience·Sebastian Poliak, Elior Peles
May 9, 2019·Physiological Reviews·Christine StadelmannMikael Simons
Oct 1, 1999·Annals of the New York Academy of Sciences·Steven S Scherer
Aug 15, 1989·The Journal of Comparative Neurology·G PanagopoulosP K Thomas

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