Associating liver partition with portal vein ligation and staged hepatectomy (ALPPS) for the treatment of liver tumors in children

Journal of Pediatric Surgery
Julio Cesar WiederkehrBarbara Aguiar Wiederkehr

Abstract

Resection is the only curative treatment option for primary and secondary malignant tumors of the liver. Although curative resection is associated with long-term survival rates, it can only be performed in 10% of patients with primary tumors and 25% of patients with liver metastases. Liver insufficiency is one of the most serious postoperative complications of patients undergoing extensive liver resections. When total liver resection is necessary liver transplant is mandatory, with the burden of long-term immunosuppression and its complications. Among several different strategies to increase the resectability of liver tumors, portal vein occlusion (embolization or ligature), bilateral tumor resection in two stages, and resection combined with loco regional therapy are the most popular. A new strategy for patients with marginally resectable liver tumors previously considered to be unresectable was formally reported by Baumgart et al. in 2011, originally developed by Hans Schlitt in 2007. This technique consists of a two-staged hepatectomy with initial portal vein ligation and in situ splitting of the liver parenchyma, and it is known as ALPPS (associating liver partition with portal vein ligation for staged hepatectomy). The aim...Continue Reading

References

Dec 5, 2006·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·K TanakaS Togo
Jul 23, 2008·The Oncologist·Jason B Litten, Gail E Tomlinson
Mar 3, 2009·American Journal of Surgery·Hai Liu, Shaihong Zhu
Apr 1, 2009·Journal of Hepato-biliary-pancreatic Surgery·Seiki Tashiro
Mar 13, 2010·Journal of Pediatric Surgery·Florent GuérinSophie Branchereau
Feb 15, 2012·Annals of Surgery·Eduardo de Santibañes, Pierre-Alain Clavien
Aug 17, 2012·Annals of Surgery·Safi Dokmak, Jacques Belghiti
Jan 21, 2014·Journal of Pediatric Surgery·Bassan J AllanJuan E Sola

❮ Previous
Next ❯

Citations

Dec 26, 2015·Journal of Pediatric Gastroenterology and Nutrition·Yi JiLi Li
Aug 18, 2020·Experimental and Clinical Transplantation : Official Journal of the Middle East Society for Organ Transplantation·Yuta HirataNaohiro Sata
Oct 4, 2018·Pediatric Transplantation·Juliet A EmamaulleeYuri Genyk
Dec 11, 2019·Cancers·Tianyou YangSanjeev A Vasudevan
Aug 28, 2020·Annals of Hepato-biliary-pancreatic Surgery·Dmitry AkhaladzeNikolay Grachev
May 16, 2019·Journal of Surgical Case Reports·Eloy Francisco Ruiz FigueroaIvan Klever Chávez Passiuri
Feb 12, 2021·Khirurgiia·D G Akhaladze

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cancer Imaging

Imaging techniques, including CT and MR, have become essential to tumor detection, diagnosis, and monitoring. Here is the latest research on cancer imaging.

Carcinoma, Hepatocellular

Hepatocellular Carcinoma is a malignant cancer in liver epithelial cells. Discover the latest research on Hepatocellular Carcinoma here.

Related Papers

Arquivos Brasileiros De Cirurgia Digestiva : ABCD = Brazilian Archives of Digestive Surgery
Orlando Jorge Martins TorresAnmara Moura Moraes
Arquivos Brasileiros De Cirurgia Digestiva : ABCD = Brazilian Archives of Digestive Surgery
Orlando Jorge Martins TorresMarcel Machado
European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
Giovanni VennarecciGiuseppe Maria Ettorre
Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract
Fernando A AlvarezE de Santibaňes
© 2021 Meta ULC. All rights reserved