Association analysis of NOTCH 4 polymorphisms with schizophrenia among two independent family based samples

American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics
S PrasadB K Thelma

Abstract

The present study investigated polymorphisms of the NOTCH 4 gene in two independent samples from India and USA, consisting of patients with schizophrenia and their parents (n = 182, and n = 148 'trios,' respectively). Five DNA markers, namely (GAAG)(n), (TAA)(n), SNP1, SNP2, and (CTG)(n) were evaluated. Transmission distortion, consistent with a modest association was detected among both samples. Additional association studies at this locus are warranted.

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Citations

Jul 2, 2009·Environmental Health and Preventive Medicine·Chikako Kiyohara, Kouichi Yoshimasu
Jan 1, 2010·Indian Journal of Psychiatry·T S Sathyanarayana RaoK S J Rao
Oct 13, 2012·International Review of Psychiatry·Prachi KukshalSmita N Deshpande
Aug 9, 2006·American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics·Zhenqi WangYan Shen
Apr 11, 2012·American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics·Christina ShayevitzStephen J Glatt

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