Abstract
Besides the classic vitamin D function on bone homeostasis, there are bodies of evidence showing that adequate status of vitamin D can modulate inflammation. We hypothesized that higher plasma levels of 25-hydroxyvitamin D (25[OH]D) would correlate with lower plasma levels of proinflammatory cytokines, acute-phase proteins, and soluble adhesion molecules and higher plasma levels of anti-inflammatory cytokines. We included all adults (age, 20-59 years) of the population-based, cross-sectional study, Health Survey-São Paulo, conducted in São Paulo (Brazil) in the study (n = 281). Anthropometric parameters, blood pressure measurements, and a fasting blood sample were collected by trained fieldworkers. Serum 25(OH)D concentration, plasma inflammatory biomarker levels (C-reactive protein, interleukin [IL]-1β, IL-6, IL-8, IL-10, tumor necrosis factor [TNF] α, IL-12p70, adiponectin, monocyte chemoattractant protein-1, soluble intercellular adhesion molecule-1, and soluble vascular cell adhesion molecule-1), and plasma blood lipid parameters were evaluated. The prevalence of vitamin D inadequacy (<50 nmol/L) was 65.5%. Inadequate participants were younger, with lower body mass index (BMI), systolic and diastolic blood pressures, trigly...Continue Reading
References
Dec 1, 2001·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·H F Deluca, M T Cantorna
Apr 3, 2002·Trends in Molecular Medicine·Chantal Mathieu, Luciano Adorini
Mar 6, 2004·The Journal of Clinical Endocrinology and Metabolism·Shamik J ParikhJack A Yanovski
Jul 28, 2005·The Journal of Steroid Biochemistry and Molecular Biology·Evelyne van Etten, Chantal Mathieu
Jan 13, 2006·European Journal of Immunology·Kambis SadeghiAndreas Spittler
Jan 18, 2008·Inflammatory Bowel Diseases·Maria MartinesiMaria Stio
Mar 6, 2008·European Journal of Nutrition·Steinar KonradsenRolf Jorde
Mar 14, 2008·Endocrine·Miriam BlumBess Dawson-Hughes
Jul 26, 2008·Journal of Inflammation·Catherine A Peterson, Mary E Heffernan
Dec 5, 2008·Medical Hypotheses·Y J Foss
Feb 4, 2010·Cytokine·Rolf JordeRoald Omdal
Mar 4, 2010·The Journal of Steroid Biochemistry and Molecular Biology·P Lips
Jul 27, 2010·Acta Physiologica·M VlasovaK H Herzig
Dec 1, 2010·Hypertension·Kristen L JablonskiDouglas R Seals
Dec 2, 2010·The Journal of Clinical Endocrinology and Metabolism·A Catharine RossSue A Shapses
Mar 16, 2011·European Journal of Endocrinology·Anand VaidyaJonathan S Williams
Mar 26, 2011·Internal and Emergency Medicine·Alfonso BelliaPaolo Sbraccia
Jul 16, 2011·Obesity·Anand VaidyaJohn P Forman
Aug 19, 2011·The British Journal of Nutrition·Marcela González-GrossUNKNOWN HELENA Study Group
Sep 9, 2011·Current Osteoporosis Reports·Jessica FieldsJeffrey I Mechanick
Oct 15, 2011·The American Journal of Cardiology·Muhammad Amer, Rehan Qayyum
Feb 11, 2012·The Journal of Nutrition·Vijay GanjiVin Tangpricha
Mar 10, 2012·Obesity·Cheryl L RockCynthia A Thomson
Oct 11, 2012·The British Journal of Nutrition·Cherlyn DingChen Bing
Nov 20, 2012·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·P O LangR Aspinall
Dec 12, 2012·Archives of Osteoporosis·D A WahlB Dawson-Hughes
Jan 22, 2013·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·P SaneeiA Esmaillzadeh
Feb 9, 2013·PLoS Medicine·Karani S VimaleswaranElina Hyppönen
Mar 26, 2013·Journal of Clinical Biochemistry and Nutrition·Misung KimCheongmin Sohn
Mar 26, 2013·PloS One·Xiaoyu Ding, Seong-Whan Lee
May 1, 2013·BMC Endocrine Disorders·Sergio Setsuo MaedaMarise Lazaretti-Castro
Jun 25, 2013·Mayo Clinic Proceedings·Arash Hossein-nezhad, Michael F Holick
Aug 13, 2013·The Journal of Nutrition, Health & Aging·V HiraniM J Seibel
Dec 12, 2013·Cancer Prevention Research·Paulette D ChandlerCharles S Fuchs
Mar 13, 2014·The Journal of Clinical Endocrinology and Metabolism·E LairdJ J Strain
Mar 25, 2014·Angiology·Edita StokićEsma Isenović
Jun 28, 2014·Journal of Inflammation Research·Kai Yin, Devendra K Agrawal
Jul 30, 2014·Frontiers in Physiology·Thea K WöbkeDieter Steinhilber
Aug 5, 2014·Age·Francesca De VitaMarcello Maggio
Nov 5, 2014·PloS One·Eliseu VerlyDirce Maria Lobo Marchioni
Dec 2, 2014·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Idoia Ibero-BaraibarM A Zulet
Citations
May 20, 2018·International Journal of Obesity : Journal of the International Association for the Study of Obesity·Gemma Carreras-BadosaAbel López-Bermejo
Aug 31, 2018·The Journal of International Medical Research·Ifigenia Kostoglou-AthanassiouPanagiotis Athanassiou
Jun 10, 2017·World Journal of Gastroenterology : WJG·Flavia A CiminiSergio Morini
Sep 12, 2019·Letters in Applied Microbiology·T L KangS Ismail
Nov 7, 2017·Mediators of Inflammation·Leticia Elizondo-MontemayorGerardo García-Rivas
Jul 9, 2020·International journal for vitamin and nutrition research. Internationale Zeitschrift für Vitamin- und Ernährungsforschung. Journal international de vitaminologie et de nutrition·Jeniffer Danielle M DutraCláudia Alves Couto
Jun 2, 2020·Diabetology & Metabolic Syndrome·Pijun YanQin Wan
Mar 14, 2020·Nutrients·Vijay GanjiXu Zhang
Apr 14, 2017·PloS One·María Elvira BalcellsRodrigo Naves
Nov 22, 2020·Irish Journal of Medical Science·Daniel M McCartneyRose Anne Kenny
Mar 23, 2021·Clinical Nutrition ESPEN·Simone BonattoRuth Liane Henn
Jul 31, 2018·Steroids·Ana Carolina MomenttiLuciana Pellegrini Pisani
Jun 13, 2021·Aging Clinical and Experimental Research·Zahra Raisi-EstabraghNicholas C Harvey