Abstract
Treating intracranial aneurysms with flow-diverting stents sometimes requires deployment of a second device. Herein we quantify the sizing effects of devices in dual-stent treatments upon the final stent microstructure and the post-treatment aneurysmal haemodynamics. Fifteen sidewall ICA aneurysm geometries were included. Using a virtual stenting technique, we implanted either one or two stents for each aneurysm treatment considered, with each stent specified as one of two different sizes, yielding a total of two single-stent and fouir dual-stent treatment scenarios for each aneurysm. Three stent microstructural parameters and nine aneurysmal haemodynamic parameters were quantified and systematically compared across the 90 treatment scenarios. Deployment of a second stent further reduced the aneurysmal inflow rate (IR) and energy loss (EL) by, respectively, 14 ± 11% (p = 0.001) and 9 ± 12% (p = 0.056), relative to the untreated condition. Sizing effects of the earlier-deployed stent led to largest differences of 6.9% for the final IR reduction and 11.1% for the EL, whereas sizing effects from the later-deployed stent were minor (≤2.1%). The change in stent pore size was the only microstructural parameter demonstrating a strong ...Continue Reading
References
Dec 15, 2010·AJNR. American Journal of Neuroradiology·P K NelsonD Fiorella
Apr 27, 2011·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·A GizziS Succi
Feb 19, 2013·Radiology·Tibor BecskePeter K Nelson
Sep 28, 2013·AJNR. American Journal of Neuroradiology·M ShapiroP K Nelson
Nov 30, 2013·AJNR. American Journal of Neuroradiology·W ChongK Mitchell
Mar 5, 2014·Frontiers in Neurology·Mario ZanatyPascal Jabbour
Apr 12, 2014·AJNR. American Journal of Neuroradiology·J R CebralD F Kallmes
Apr 26, 2014·AJNR. American Journal of Neuroradiology·D MaH Meng
Sep 5, 2014·Annals of Biomedical Engineering·Bongjae Chung, Juan Raul Cebral
Mar 10, 2015·Journal of Biomechanics·Umberto MorbiducciDavid A Steinman
Jul 15, 2015·Journal of Biomechanics·Robert J DamianoHui Meng
Jul 29, 2015·Journal of Neurointerventional Surgery·Daniel Ribeiro de SousaKarim Zouaoui Boudjeltia
Aug 5, 2015·Annals of Biomedical Engineering·T W PeachY Ventikos
Dec 15, 2015·Computer Methods in Applied Mechanics and Engineering·K SprangerY Ventikos
Jul 9, 2016·AJNR. American Journal of Neuroradiology·A RouchaudR Kadirvel
Jan 7, 2017·AJNR. American Journal of Neuroradiology·R J DamianoH Meng
Jun 4, 2017·Journal of Biomechanics·Mingzi ZhangYi Qian
Jul 12, 2017·Medical Engineering & Physics·Daniele BianchiGiuseppe Vairo
Oct 25, 2017·Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society· Mingzi Zhang Yi Qian
Sep 24, 2018·Journal of Biomechanics·C ChnafaD A Steinman
Mar 31, 2019·Journal of Neurointerventional Surgery·Matthew James KoleDheeraj Gandhi
Sep 29, 2019·AJNR. American Journal of Neuroradiology·B W ChongG Lanzino