Association between anterior ST depression and increased myocardial salvage following reperfusion therapy in patients with inferior myocardial infarction

The American Journal of Medicine
M A EvansRaymond J Gibbons

Abstract

To determine electrocardiographic features associated with myocardial salvage following reperfusion therapy in patients with inferior myocardial infarction. Ninety-two consecutive patients with acute inferior myocardial infarction were treated with reperfusion therapy in a tertiary care center. Several features were measured on the presenting electrocardiogram, including the presence or absence of ST depression in the chest leads and the total magnitudes of ST elevation or depression, and were then evaluated for their association with myocardial salvage. Myocardial salvage (% of left ventricle) was the difference between myocardium at risk and final infarct size. Tomographic myocardial perfusion imaging with technetium-99m sestamibi was performed acutely to measure myocardium at risk and repeated prior to hospital discharge to measure final infarct size. The amount of myocardium at risk of infarction in the 92 patients was 19.1%+/-11.3% (range 1% to 68%), and the final infarct size was 10.6%+/-10.0% (range 0% to 45%). Thus, myocardial salvage in the 92 patients was 8.5%+/-8.4% (range -11% to 35%) of the left ventricle, or 0.51+/-0.38 (range 0.0 to 1.0) when expressed as a fraction of the myocardium at risk (salvage index). The ...Continue Reading

References

May 1, 1991·Journal of the American College of Cardiology·T F ChristianB J Gersh
Oct 1, 1991·Mayo Clinic Proceedings·I P ClementsR J Gibbons
Feb 1, 1990·Circulation·P B Berger, T J Ryan
Jan 1, 1983·Catheterization and Cardiovascular Diagnosis·M HaraphongseR E Rossall
Jan 15, 1994·The American Journal of Cardiology·J J EdmundsI P Clements

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