Association between aortic stiffness and left ventricular function in inflammatory bowel disease

Cardiology Journal
Abdullah N AslanEngin Bozkurt

Abstract

Recent studies have reported an increased incidence of both aortic stiffness and left ventricular (LV) systolic and diastolic dysfunction in patients with inflammatory bowel disease (IBD). However, the association between aortic stiffness and the LV function has not been fully defined. We aimed to investigate the relationship between aortic stiffness and the LV function in IBD patients. Seventy-two patients with IBD (56 cases of ulcerative colitis and 16 cases of Crohn's disease) and 50 healthy controls were consecutively enrolled in this study. The LV systolic and diastolic functions were assessed using conventional echocardiographic techniques, including tissue Doppler echocardiography. The degree of aortic strain and distensibility were calculated based on the aortic diameters measured on M-mode echocardiography at thelevel of 3 cm above the aortic valve and the blood pressure values obtained on sphygmomanometry. There were significant differences between the IBD and control group in the degree of aortic strain and distensibility. Significant differences were also observed between the patient and control groups in the parameters of the LV systolic and diastolic functions. Moreover, aortic stiffness was found to be associated...Continue Reading

Citations

Oct 12, 2017·Journal of the American Heart Association·Luca ZanoliStephane Laurent
Feb 9, 2019·Gastroenterology Research and Practice·Diana-Maria BunuDaniela-Maria Tanase
Feb 5, 2019·Journal of the American Heart Association·Luca ZanoliPierre Boutouyrie
Sep 24, 2020·Journal of Digestive Diseases·Cenk SariErsin Çağrı Şimşek

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