Association between assisted reproductive technology conception and autism in California, 1997-2007

American Journal of Public Health
Christine FountainPeter Bearman

Abstract

We assessed the association between assisted reproductive technology (ART) and diagnosed autistic disorder in a population-based sample of California births. We performed an observational cohort study using linked records from the California Birth Master Files for 1997 through 2007, the California Department of Developmental Services autism caseload for 1997 through 2011, and the Centers for Disease Control and Prevention's National ART Surveillance System for live births in 1997 through 2007. Participants were all 5 926 251 live births, including 48 865 ART-originated infants and 32 922 cases of autism diagnosed by the Department of Developmental Services. We compared births originated using ART with births originated without ART for incidence of autism. In the full population, the incidence of diagnosed autism was twice as high for ART as non-ART births. The association was diminished by excluding mothers unlikely to use ART; adjustment for demographic and adverse prenatal and perinatal outcomes reduced the association substantially, although statistical significance persisted for mothers aged 20 to 34 years. The association between ART and autism is primarily explained by adverse prenatal and perinatal outcomes and multiple ...Continue Reading

References

Nov 26, 1999·JAMA : the Journal of the American Medical Association·L A SchieveL S Wilcox
Mar 8, 2002·The New England Journal of Medicine·Laura A SchieveLynne S Wilcox
Jul 3, 2002·Epidemiology·Christina M HultmanSven Cnattingius
Jul 11, 2002·Journal of Autism and Developmental Disorders·Lisa A CroenSteve Selvin
Jul 11, 2002·Journal of Autism and Developmental Disorders·Lisa A CroenSteve Selvin
Jun 3, 2004·Obstetrics and Gynecology·Laura A SchieveVictoria C Wright
Jan 25, 2005·Human Reproduction·Christina Bergh
May 5, 2005·American Journal of Epidemiology·Heidi Jeanet LarssonPreben Bo Mortensen
Dec 2, 2005·Journal of Perinatology : Official Journal of the California Perinatal Association·A ItoY Nakamura
Mar 9, 2007·Maternal and Child Health Journal·Laura A SchieveUNKNOWN Massachusetts Consortium for Assisted Reproductive Technology Epidemiologic Research (MCARTER)
Apr 4, 2007·Archives of Pediatrics & Adolescent Medicine·Lisa A CroenJudith K Grether
Apr 21, 2007·Fertility and Sterility·Judy E SternUNKNOWN Society for Assisted Reproductive Technology Writing Group
Apr 26, 2007·Human Reproduction·Rikke Damkjaer Maimburg, Michael Vaeth
Oct 24, 2008·American Journal of Epidemiology·Maureen S DurkinLaura A Schieve
Apr 11, 2009·Autism Research : Official Journal of the International Society for Autism Research·Kim Van Naarden BraunJennifer Pinto-Martin
Jul 18, 2009·American Journal of Public Health·Marissa D KingPeter S Bearman
Jun 30, 2010·Journal of Epidemiology and Community Health·D HvidtjørnP Thorsen
Nov 3, 2010·American Journal of Epidemiology·Tyler J Vanderweele, Stijn Vansteelandt
May 7, 2011·American Sociological Review·Marissa D King, Peter S Bearman
Jun 11, 2011·Research in Developmental Disabilities·Ditza A Zachor, E Ben Itzchak
Sep 16, 2011·JAMA : the Journal of the American Medical Association·Eli Y Adashi, Ron Wyden
Dec 27, 2011·Fertility and Sterility·UNKNOWN Practice Committee of Society for Assisted Reproductive Technology, UNKNOWN Practice Committee of American Society for Reproductive Medicine
Jun 13, 2012·Paediatric and Perinatal Epidemiology·Kristen LyallAlberto Ascherio
Jul 4, 2013·JAMA : the Journal of the American Medical Association·Sven SandinAbraham Reichenberg
Jul 9, 2013·BMJ : British Medical Journal·Bjørn BayUlrik Schiøler Kesmodel
Aug 24, 2013·International Journal of Environmental Research and Public Health·Kristen LyallCheryl K Walker
May 21, 2014·Fertility and Sterility·Sean AckermanRaphael Bernier

❮ Previous
Next ❯

Citations

Jan 31, 2016·Reproduction : the Official Journal of the Society for the Study of Fertility·Kun TanJianhui Tian
Dec 4, 2015·MMWR. Surveillance Summaries : Morbidity and Mortality Weekly Report. Surveillance Summaries·Saswati SunderamWanda D Barfield
Feb 10, 2017·MMWR. Surveillance Summaries : Morbidity and Mortality Weekly Report. Surveillance Summaries·Saswati SunderamWanda D Barfield
Jan 10, 2017·Annual Review of Public Health·Kristen LyallCraig Newschaffer
Feb 17, 2018·American Journal of Epidemiology·Ran S RotemMarc G Weisskopf
Feb 13, 2019·Human Reproduction Update·Sine BerntsenAnja Pinborg
Feb 2, 2019·The Journal of Endocrinology·Miguel A VelazquezAdam J Watkins
Nov 21, 2017·Autism : the International Journal of Research and Practice·For-Wey LungBih-Ching Shu
Apr 26, 2019·MMWR. Surveillance Summaries : Morbidity and Mortality Weekly Report. Surveillance Summaries·Saswati SunderamWanda D Barfield
Feb 16, 2018·MMWR. Surveillance Summaries : Morbidity and Mortality Weekly Report. Surveillance Summaries·Saswati SunderamWanda D Barfield
Dec 18, 2020·MMWR. Surveillance Summaries : Morbidity and Mortality Weekly Report. Surveillance Summaries·Saswati SunderamWanda D Barfield

❮ Previous
Next ❯

Related Concepts

Related Feeds

Autism

Autism spectrum disorder is associated with challenges with social skills, repetitive behaviors, and often accompanied by sensory sensitivities and medical issues. Here is the latest research on autism.