Jan 26, 2013

Association between atrial fibrillatory rate and heart rate variability in patients with atrial fibrillation and congestive heart failure

Annals of Noninvasive Electrocardiology : the Official Journal of the International Society for Holter and Noninvasive Electrocardiology, Inc
Valentina D A CorinoPyotr G Platonov

Abstract

Even if atrial fibrillatory rate (AFR) has been related to clinical outcome in patients with atrial fibrillation (AF), its relation with ventricular response has not been deeply studied. The aim of this study was to investigate the relation between AFR and RR series variability in patients with AF. Twenty-minute electrocardiograms in orthogonal leads were processed to extract AFR, using spatiotemporal QRST cancellation and time frequency analysis, and RR series in 127 patients (age 69 ± 11 years) with congestive heart failure (NYHA II-III) enrolled in the MUSIC study (MUerte Subita en Insufficiencia Cardiaca). Heart rate variability and irregularity were assessed by time domain parameters and entropy-based indices, respectively and their correlation with AFR investigated. Variability measures seem not to be related to AFR, while irregularity measures do. A significant correlation between AFR and variability parameters of heart rate variability during AF was found only in patients not treated with antiarrhythmics drugs (correlation = 0.56 P < 0.05 for pNN50), while this correlation was lost in patients taking rate- or rhythm-control drugs. A significant positive correlation between AFR and indices of RR irregularity was found, s...Continue Reading

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Mentioned in this Paper

Central Lobule of Cerebellum
Anti-Arrhythmia Agents
Atrial Fibrillation
Longitudinal Survey
Heart Ventricle
Heart Atrium
Subgroup A Nepoviruses
Myocardial Failure
Electrocardiographic Recorders
Xeroderma Pigmentosum, Variant Type

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