Association between bruxism and symptomatic gastroesophageal reflux disease: A case-control study

Journal of Dentistry
Yuanyuan LiJihua Chen

Abstract

To examine the relation between bruxism and gastroesophageal reflux disease (GERD) and the contribution of depression, anxiety and impaired sleep quality to that association. A three-centre case-control study was conducted consisting of 887 consecutive clinically-diagnosed bruxism patients aged 18-75 years and 887 matched controls. Diagnosis of GERD was based on the Montreal definition: moderate/severe symptoms ≥ one day/week or mild symptoms ≥ two days/week. Logistic regression was used to evaluate the association between bruxism and GERD. Mediation analyses were used to test whether the association between bruxism and GERD was mediated by depression, anxiety or impaired sleep quality. Binary logistic regression identified that GERD was associated with bruxism (odds ratio, 6.87; 95% confidence interval (CI), 4.34-10.88). This association was stronger in females (odds ratio, 12.27; 95% CI, 5.81-25.91) than in males (odds ratio, 3.99; 95% CI, 2.17-7.32). Multinomial logistic regression identified that GERD was associated with all types of bruxism (sleep bruxism alone, odds ratio, 6.71, 95% CI, 4.22-10.68; awake bruxism alone, odds ratio, 13.06, 95% CI, 5.32-32.05; overlap of sleep bruxism and awake bruxism, odds ratio, 6.48, 95%...Continue Reading

Citations

Nov 9, 2018·Journal of Clinical Medicine·Yuanyuan LiJihua Chen
Jun 20, 2020·The Journal of Clinical Pediatric Dentistry·E Calvano KüchlerK Diaz-Serrano
May 15, 2021·Sleep Medicine Clinics·Thomas Bornhardt, Veronica Iturriaga

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