Association between Celiac Disease and Chronic Hepatitis C Virus Infection

Journal of Clinical and Experimental Hepatology
Ashish GargRadha K Dhiman

Abstract

Celiac disease affects the proximal small intestine and is caused by a local immune response to dietary gluten. Celiac disease usually presents with chronic diarrhea; however, presentations with elevated hepatic transaminase levels in blood or with iron-deficiency anemia have been described. Celiac disease has been reported to be associated with autoimmune liver diseases. Hepatitis C virus (HCV) can also initiate autoimmune disease process. Therefore, HCV infection and celiac disease may occur together. Here, we describe 4 cases of celiac disease associated with chronic hepatitis C. This small case series indicates that chronic HCV infection and celiac disease are not causally associated.

Citations

Aug 29, 2019·Current Pharmaceutical Biotechnology·Aref ShariatiTaher Azimi
Sep 26, 2012·Clinical & Developmental Immunology·Tamara Pozo-RubioYolanda Sanz
Aug 22, 2018·Nutrients·Xuechen B YuArmin Alaedini
Sep 15, 2018·Nature Reviews. Gastroenterology & Hepatology·Alberto CamineroElena F Verdu

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