Association between Chronic Kidney Disease and Risk of Cataract: A Nationwide Retrospective Cohort Study

American Journal of Nephrology
Yin-Tzu LiuYung-Cheng Su

Abstract

Previous studies have established a relationship between chronic kidney disease (CKD) and cataract, but the relationship between the severity of renal impairment and risk of cataract is uncertain. This study investigates the relationship between the severity of renal disease and cataract in a nationwide sample from Taiwan. The cohort from 1-million National Health Insurance beneficiaries from Taiwan was retrospectively analyzed. All adult beneficiaries were followed from January 1, 2005 until December 31, 2013, to identify patients who underwent cataract surgeries. On the basis of the ambulatory care records, those diagnosed with CKD (ICD-9-CM code: 585) during the follow-up period were enrolled as CKD patients after careful evaluation. Each patient with CKD was age- and gender-matched with 4 individuals who did not have CKD. Cox regression models were applied to compare the hazard of cataract surgery in individuals with and without CKD. Subgroup analysis was used to compare patients with end-stage renal disease (ESRD) with age- and gender-matched non-CKD individuals. ESRD was defined by CKD patients who need regular renal replacement therapy. The same method was applied to evaluate hazard ratios (HRs). After age and gender mat...Continue Reading

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Citations

May 22, 2017·American Journal of Nephrology·Heather G Mack, Judy Savige
Jan 12, 2021·Clinical & Experimental Ophthalmology·Michael J Ang, Natalie A Afshari

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