Association between delirium, adverse clinical events and functional outcomes in older patients admitted to rehabilitation settings after a hip fracture: A multicenter retrospective cohort study

Geriatrics & Gerontology International
Alessandro MorandiGiuseppe Bellelli

Abstract

The aim of the present study is to investigate how delirium and adverse clinical events (ACE) contribute independently and in combination to functional outcomes in older patients admitted to rehabilitation settings after a hip fracture. This is a multicenter retrospective cohort study of patients aged ≥65 years admitted after hip fracture surgical repair to three Italian rehabilitation units. Delirium on admission was evaluated with the Confusion Assessment Method. ACE during the rehabilitation stay were recorded, including infections (i.e. urinary tract infections, other infections), non-infectious ACE (i.e. cardiovascular events, respiratory failure, pulmonary embolism) and falls. A multivariable linear regression was used to evaluate the effect of ACE and delirium on functional outcome, adjusting for covariates determined a priori. A total of 519 patients were included in the study. The mean ± SD age was 82.9 ± 9.4 years. ACE occurred in 277 patients (53.4%), delirium alone was present in 19 patients (3.6%). Both conditions were present in 58 patients (11.2%). Compared with patients without delirium or ACE, those with ACE or delirium were more likely to have a worse functional outcome (-6.7 Barthel Index points [-11.6; -1.7]...Continue Reading

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Citations

Apr 4, 2021·International Journal of Environmental Research and Public Health·Francisco José Tarazona-SantabalbinaJosé Ramón Caeiro
Apr 29, 2021·International Journal of Geriatric Psychiatry·Chiara Maria GandossiGiuseppe Bellelli
Jul 22, 2021·Aging Clinical and Experimental Research·Antonio De VincentisUNKNOWN Istituto Superiore Sanità (ISS)
Jun 26, 2021·JPEN. Journal of Parenteral and Enteral Nutrition·Melody Xuan En FooCharles Chin Han Lew

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