Association Between Depression and Outcomes in Chinese Patients With Myocardial Infarction and Nonobstructive Coronary Arteries

Journal of the American Heart Association
Xiao-Hong GuBin Han

Abstract

Background Myocardial infarction with nonobstructive coronary arteries ( MINOCA ) occurs in ≈10% of all patients with myocardial infarction. Studies on effects of depression on MINOCA outcomes are lacking. Therefore, the aim of this study was to examine the association of depression with clinical outcomes in Chinese patients with MINOCA . Methods and Results We conducted a prospective cohort study of 633 participants with MINOCA and followed up for 3 years. End points were defined as all-cause mortality and cardiovascular events. Diagnosis of depression was ascertained using the psychiatric interview based on the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5). During the follow-up period, all-cause death occurred in 93 individuals and cardiovascular events developed in 170 individuals. Kaplan-Meier curves showed a significant association of depression with all-cause mortality (log-rank P<0.001) and cardiovascular events (log-rank P<0.001). Multiple Cox regression identified the new diagnosis of depression as an independent prognostic factor for all-cause mortality as well as cardiovascular events (adjusted hazard ratio, 7.250; 95% CI, 4.735-11.100; P<0.001; and hazard ratio, 3.411; 95% CI , 2.490-4...Continue Reading

References

Feb 1, 1960·Journal of Neurology, Neurosurgery, and Psychiatry·M HAMILTON
Feb 11, 2005·The New England Journal of Medicine·Ilan S WittsteinHunter C Champion
Jan 21, 2006·Journal of General Internal Medicine·Brett D ThombsRoy C Ziegelstein
Aug 11, 2006·Journal of General Internal Medicine·Ian M KronishKarina W Davidson
Oct 31, 2006·American Heart Journal·Nina RieckmannKarina W Davidson
Sep 22, 2007·Journal of Hypertension·David A BartonGavin W Lambert
Nov 27, 2008·JAMA : the Journal of the American Medical Association·Mary A WhooleyWarren S Browner
Mar 18, 2010·Psychotherapy and Psychosomatics·Sujung J YoonIn Kyoon Lyoo
Mar 27, 2013·Archives of Cardiovascular Diseases·Jean-Christophe Chauvet-GélinierBernard Bonin
Jun 13, 2015·Indian Journal of Pharmacology·Krishna UndelaSharon Sunny John
Nov 26, 2015·Circulation Journal : Official Journal of the Japanese Circulation Society·Sivabaskari PasupathyJohn F Beltrame
Feb 24, 2016·Health Psychology : Official Journal of the Division of Health Psychology, American Psychological Association·Ricardo de Miranda AzevedoPeter de Jonge
Dec 9, 2017·Circulation. Cardiovascular Quality and Outcomes·Tanya S KenkreSheryl F Kelsey

❮ Previous
Next ❯

Software Mentioned

MINOCA
SPSS

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.