Association between diabetes and increased prevalence of paranasal sinus disease: a cross-sectional study in Japanese adults

Journal of Epidemiology
Yusuke KabeyaAkira Shimada

Abstract

The association between diabetes and paranasal sinus disease has not been thoroughly investigated. We cross-sectionally investigated the association between diabetes and the presence of paranasal sinus disease, which was confirmed by a head MRI scan in 1350 adults who underwent a health screening program focusing on brain diseases and metabolic syndrome. Logistic regression, which was adjusted for age, sex, body mass index, waist-to-hip ratio, hypertension, smoking status, alcohol intake, and white blood cell count, was performed to calculate the odds ratio (OR) of having paranasal sinus disease among adults with diabetes in relation to those without. The dose-response relationship between hemoglobin A1c (HbA1c) levels and the presence of paranasal sinus disease was also investigated. Of the 1350 participants (mean age, 61.6 ± 10.0 years; 71.6% men), 220 diabetes cases were identified. Paranasal sinus disease was diagnosed in 151 adults. The adjusted OR of having paranasal sinus disease was 1.74 (95% confidence interval [CI], 1.12-2.71) in those with diabetes. The odds of having paranasal sinus disease increased with HbA1c levels. Compared to those with HbA1c of ≤5.4%, those with HbA1c of 5.5%-6.4%, 6.5%-7.9%, and ≥8.0% were mo...Continue Reading

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Citations

Feb 3, 2016·Journal of Epidemiology·Yusuke KabeyaAkira Shimada
Jul 19, 2017·American Journal of Rhinology & Allergy·Eun Jung LeeKyung-Su Kim
Oct 5, 2019·QJM : Monthly Journal of the Association of Physicians·S-Y LiC-H Kao
Jun 12, 2020·Physical and Engineering Sciences in Medicine·Usharani ThirunavukkarasuRavichandran Thirunavukkarasu
Nov 3, 2021·Clinical Otolaryngology : Official Journal of ENT-UK ; Official Journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery·Jae-Sung NamHyung-Ju Cho

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