Association between dietary factors and plasma fetuin-A concentrations in the general population

The British Journal of Nutrition
Katharina NimptschJakob Linseisen

Abstract

Circulating fetuin-A, a novel marker for hepatic fat accumulation, has been related to a higher risk of type 2 diabetes and cardiovascular diseases in a growing number of prospective studies. However, little is known about dietary determinants of fetuin-A concentrations in the general population. Therefore, we aimed to investigate the association between dietary intake of energy, energy-providing nutrients, alcohol and major food groups and plasma fetuin-A concentrations in the Bavarian Food Consumption Survey II. Dietary intake was assessed by three 24-h dietary recalls, and plasma concentrations of fetuin-A were measured in 558 adults (18-81 years). After multivariable adjustment for lifestyle factors and body fatness, higher energy intake was nonsignificantly associated with higher fetuin-A concentrations (per 2092 kJ/d (500 kcal/d) 3·7 µg/ml, 95 % CI -0·5, 7·8 µg/ml). There was no clear association between energy-providing nutrients and fetuin-A concentrations. Higher alcohol intake was associated with lower fetuin-A concentrations (P trend 0·003): mean fetuin-A concentrations were 324 (95 % CI 313, 335) µg/ml in non-drinkers, and with 293 (95 % CI 281, 306) µg/ml significantly lower in participants who drank ≥30 g alcohol ...Continue Reading

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Citations

Jan 8, 2016·Biochimie·Katie N Robinson, Margarita Teran-Garcia
Dec 16, 2016·International Journal of Molecular Sciences·Salvatore PettaFerruccio Bonino
Nov 11, 2017·Clinical Nutrition Research·Farzad RoshanzamirSeyyed Morteza Safavi
Jun 25, 2019·Critical Reviews in Food Science and Nutrition·Mehmet Arif Icer, Hilal Yıldıran
Nov 28, 2020·Clinical Biochemistry·Mehmet Arif Icer, Hilal Yıldıran

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