Association between dietary patterns and prognosis of hepatocellular carcinoma in the Guangdong Liver Cancer Cohort Study

Hepatology Research : the Official Journal of the Japan Society of Hepatology
Yun LuoHui-Lian Zhu

Abstract

Adherence to dietary recommendations has been linked to a reduced risk of developing hepatocellular carcinoma (HCC) and dying of chronic liver disease, but its role in the prognosis of HCC is still unclear. We prospectively investigated the association of two dietary quality indices, the Chinese Healthy Eating Index (CHEI) and the Healthy Eating Index-2015 (HEI-2015), with all-cause and HCC-specific mortality in a large prospective cohort of HCC survivors. We included 887 patients with newly-diagnosed, previously untreated HCC enrolled in the Guangdong Liver Cancer Cohort (GLCC) between September 2013 and April 2017 in the analysis. CHEI and HEI-2015 scores were calculated based on the dietary intake in the year before diagnosis of HCC. Cox proportional hazards regression models were used to estimate multivariable hazard ratios (HRs) and 95% confidence intervals (CIs) for each index. During a median follow-up of 797 days, 389 deaths were identified, including 347 from HCC. Higher CHEI scores, reflecting favorable adherence to the 2016 Dietary Guidelines for Chinese, were associated with a lower risk of all-cause mortality (T3 vs. T1 : HR=0.75, 95% CI: 0.58-0.98) and HCC-specific mortality (T3 vs. T1 : HR=0.74, 95% CI: 0.56-0.98...Continue Reading

References

Jul 6, 2000·Cancer Causes & Control : CCC·R A BreslowA F Subar
Sep 26, 2006·International Journal of Cancer. Journal International Du Cancer·Renato TalaminiSilvia Franceschi
Aug 24, 2010·Journal of the National Cancer Institute·Neal D FreedmanRashmi Sinha
Nov 30, 2011·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Yael GoldfarbShamgar Ben-Eliyahu
Nov 6, 2012·Annals of Oncology : Official Journal of the European Society for Medical Oncology·V FedirkoM Jenab
May 15, 2013·Annals of Oncology : Official Journal of the European Society for Medical Oncology·V FedirkoM Jenab
Nov 19, 2013·Journal of Hepatology·Federica TuratiPagona Lagiou
Apr 10, 2014·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Wen-Qing LiNeal D Freedman
Dec 2, 2014·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Kerstin SchüttePeter Malfertheiner
May 15, 2015·European Journal of Clinical Nutrition·L-G ZhaoY-B Xiang
Aug 28, 2015·Metallomics : Integrated Biometal Science·Delphine DenoyerMichael A Cater
Mar 30, 2016·Annual Review of Nutrition·Carmen Sapienza, Jean-Pierre Issa
Jul 13, 2016·Gastrointestinal Tumors·Kerstin SchüttePeter Malfertheiner
Jan 13, 2017·Nature·Nadja S KathederTor Erik Rusten
Oct 5, 2017·Cancer Control : Journal of the Moffitt Cancer Center·Ashok ShianiMark Friedman
Nov 8, 2017·Current Biology : CB·Elijah TreftsDavid H Wasserman
Aug 28, 2018·Journal of the Academy of Nutrition and Dietetics·Susan M Krebs-SmithJill Reedy
Aug 28, 2018·Journal of the Academy of Nutrition and Dietetics·Jill ReedyJanet A Tooze
Nov 15, 2018·International Journal of Cancer. Journal International Du Cancer·Ai-Ping FangHui-Lian Zhu
Dec 7, 2018·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Yanan MaXuehong Zhang
Jan 20, 2019·Journal of Hepatology·Nathalie Ganne-Carrié, Pierre Nahon
Feb 1, 2013·Annals of Oncology : Official Journal of the European Society for Medical Oncology·V FedirkoM Jenab

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Citations

Oct 29, 2021·Food & Function·Dinuerguli YishakeHui-Lian Zhu

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