Association between Frailty, Osteoporosis, Falls and Hip Fractures among Community-Dwelling People Aged 50 Years and Older in Taiwan: Results from I-Lan Longitudinal Aging Study

PloS One
Li-Kuo LiuLiang-Kung Chen

Abstract

Association of frailty with adverse clinical outcomes has been reported in Western countries, but data from the Asian population are scarce. This study aimed to evaluate the epidemiology of frailty among community-dwelling middle-aged and elderly population and to explore its association with musculoskeletal health in Taiwan. I-Lan Longitudinal Aging Study (ILAS) data were retrieved for this study. Frailty was defined by the Fried's criteria; a comparison of demographic characteristics, physical performance, and body composition, including skeletal muscle mass and bone mineral density (BMD), as well as recent falls, history of hip fractures and the functional status of subjects with different frailty statuses were accomplished. Overall, the data of 1,839 participants (mean age: 63.9±9.3 years, male 47.5%) were obtained for analysis. The prevalence of pre-frailty was 42.3% in men and 38.8% in women, whereas the prevalence of frailty was 6.9% and 6.7% in men and women, respectively. Frailty was significantly associated with older age, the male gender, larger waist circumference, lower skeletal muscle index, lower hip BMD, poorer physical function, poorer nutritional status, and poorer cognitive function. Also, frailty was signifi...Continue Reading

References

Mar 5, 1998·JAMA : the Journal of the American Medical Association·L P FriedJ M Gardin
Mar 17, 2001·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·L P FriedUNKNOWN Cardiovascular Health Study Collaborative Research Group
Sep 6, 2003·Age and Ageing·Julia L NewtonRoger M Francis
Feb 14, 2004·Journal of the American Geriatrics Society·Angela M AbbatecolaGiuseppe Paolisso
Mar 20, 2004·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Linda P FriedGerard Anderson
Apr 13, 2004·Medicine and Science in Sports and Exercise·Pedro Curi Hallal, Cesar Gomes Victora
Oct 9, 2004·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·John E Morley, Richard N Baumgartner
May 12, 2006·Journal of the American Geriatrics Society·Marianne B van Iersel, Marcel G M Olde Rikkert
Sep 12, 2006·The Medical Clinics of North America·John E MorleyMoon Jong Kim
Jul 31, 2007·Journal of the American Geriatrics Society·Peggy M CawthonUNKNOWN Osteoporotic Fractures in Men Research Group
Sep 4, 2007·The American Journal of Medicine·Nasiya AhmedMindy J Fain
Apr 30, 2008·The Journal of Nutrition, Health & Aging·Y RollandB Vellas
Nov 28, 2009·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Ruth E HubbardKenneth Rockwood
Feb 23, 2010·Archives of Gerontology and Geriatrics·Chin-Ying ChenBee-Horng Lue
Apr 7, 2010·Nursing Outlook·Robbert J GobbensJos M Schols
Apr 16, 2010·Age and Ageing·Alfonso J Cruz-JentoftUNKNOWN European Working Group on Sarcopenia in Older People
Jun 1, 2010·Journal of the American College of Surgeons·Martin A MakaryLinda P Fried
May 13, 2011·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·E Y N CheungA Kung
Feb 1, 2012·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·C CooperJ-Y L Reginster
Feb 10, 2012·Journal of the American Geriatrics Society·Krupa ShahWilliam J Hall
Mar 20, 2012·Ageing Research Reviews·Tatyana ShamliyanRobert L Kane
Aug 4, 2012·Archives of Gerontology and Geriatrics·Pilar JürschikMaria Viladrosa
Jan 29, 2013·Journal of the American Geriatrics Society·Sarah E TomUNKNOWN GLOW Investigators
Feb 5, 2013·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Julie A WomackUNKNOWN Veterans Aging Cohort Study Project Team
Feb 15, 2013·Journal of the American Geriatrics Society·Cheng-Chieh LinTsai-Chung Li
May 8, 2013·Journal of Renal Nutrition : the Official Journal of the Council on Renal Nutrition of the National Kidney Foundation·Cynthia DelgadoKirsten L Johansen
May 10, 2013·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Vasant HiraniMarkus J Seibel
May 15, 2013·Journal of the American Medical Directors Association·Hiroyuki ShimadaTakao Suzuki
Jun 22, 2013·The Journal of Clinical Endocrinology and Metabolism·Yuen Y E WongLeon Flicker
Sep 5, 2013·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·S A SternbergJ Menczel
Sep 7, 2013·American Journal of Epidemiology·Timo E StrandbergReijo S Tilvis
Apr 8, 2014·Joint, Bone, Spine : Revue Du Rhumatisme·Hubert BlainUNKNOWN Groupe de recherche et d’information sur les ostéoporoses et la Société française de gérontologie et gériatrie
Nov 6, 2014·Journal of the American Geriatrics Society·Hee-Won JungKwang-il Kim

❮ Previous
Next ❯

Citations

Feb 28, 2017·Journal of the American Medical Directors Association·Sjors VerlaanMarian A E de van der Schueren
Feb 1, 2017·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Nicola VeroneseSarah E Lamb
Nov 6, 2018·American Journal of Hypertension·Shao-Yuan ChuangPei-Ning Wang
Jun 21, 2018·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Hung Cao DinhUNKNOWN Gerontopole Brussels Study Group
Jan 30, 2019·Rejuvenation Research·Xue-Lian SunBi-Rong Dong
Oct 5, 2017·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Ting-Ching TangLiang-Kung Chen
Feb 23, 2020·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Irene Rodríguez-GómezIgnacio Ara
Feb 14, 2019·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Andreas LodbergMarco Eijken
Aug 4, 2020·Health & Social Care in the Community·Angela Yee Man LeungRenli Deng
Jul 18, 2017·PeerJ·Chia-Ter ChaoUNKNOWN Cohort of Geriatric Nephrology in NTUH (COGENT) study group
Jul 4, 2020·Calcified Tissue International·Monica C TemboJulie A Pasco
Jun 28, 2018·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·P BartoschK E Akesson
Jun 7, 2020·BMC Geriatrics·Monica C TemboJulie A Pasco
Oct 23, 2019·Geriatrics & Gerontology International·Masahiro TadaNoriaki Hidaka
Jan 18, 2020·BMC Geriatrics·Mandy M ArchibaldMellick J Chehade
Apr 16, 2020·Nutrients·Pilar Pérez-RosFrancisco Miguel Martínez-Arnau
Nov 30, 2018·Journal of Clinical Medicine·Chi Hsien HuangKuang-Ming Kuo
May 21, 2021·Calcified Tissue International·Monica C TemboJulie A Pasco

❮ Previous
Next ❯

Methods Mentioned

BETA
ELISA
X-ray

Related Concepts

Related Feeds

Epidemiology of Aging

This feed focuses on epidemiology of aging and aging-related conditions, including Alzheimer’s disease, dementia, and age-associated cognitive impairment. Here is the latest research.