Association Between Gestational Hypertension and Risk of Cardiovascular Disease Among 617 589 Norwegian Women

Journal of the American Heart Association
Hilde Kristin Refvik RiiseAnne Kjersti Daltveit

Abstract

Preeclampsia and gestational hypertension (GH) are the most common hypertensive pregnancy disorders. Preeclampsia has been linked to increased risk of cardiovascular disease (CVD), but a similar association for GH has not been established. We aimed to determine the association between GH and subsequent CVD, and explore the additional role of small-for-gestational-age infants, preterm delivery, and parity. Data from the Medical Birth Registry of Norway were linked to the Cardiovascular Disease in Norway project and the Norwegian Cause of Death Registry. Hazard ratios and 95% confidence intervals were computed using Cox proportional hazard regression, comparing women with and without GH during their first and/or second pregnancy. We included all women with a first delivery from 1980 through 2009 (n=617 589) and followed them for a median of 14.3 (quartile 1-quartile 3: 6.9-21.5) years. Women with GH in the first pregnancy had 1.8-fold (95% confidence interval, 1.7-2.0) higher risk of subsequent CVD compared with women without any hypertensive pregnancy disorder. When GH occurred in combination with small-for-gestational-age infants and/or preterm delivery, the hazard ratio was 2.6 (95% confidence interval, 2.3-3.0). When women wi...Continue Reading

References

Nov 1, 1995·Acta Obstetricia Et Gynecologica Scandinavica·L S JónsdóttirN Sigfússon
Jun 17, 2000·Acta Obstetricia Et Gynecologica Scandinavica·R SkjaervenL S Bakketeig
Nov 24, 2001·BMJ : British Medical Journal·H U IrgensR T Lie
Jan 26, 2002·American Journal of Obstetrics and Gynecology·Alan BuchbinderUNKNOWN National Institute of Child Health and Human Development Network of Maternal-Fetal Medicine Units
Apr 19, 2003·BMJ : British Medical Journal·Brenda J WilsonW Cairns S Smith
Oct 29, 2003·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Bryan KestenbaumStephen M Schwartz
Oct 18, 2005·BJOG : an International Journal of Obstetrics and Gynaecology·Anna-Karin WikströmSolveig Nordén Lindeberg
Jun 23, 2009·BMJ : British Medical Journal·Sonia Hernández-DíazSven Cnattingius
Sep 30, 2009·The American Journal of Medicine·Scott R YoderJohn D Bisognano
Jul 14, 2010·Paediatric and Perinatal Epidemiology·Jacob A LykkeMichael J Paidas
Nov 29, 2012·BMJ : British Medical Journal·Rolv SkjaervenRolv Terje Lie
Feb 12, 2013·European Journal of Epidemiology·Morven Caroline BrownRuth Bell
Apr 30, 2013·Acta Obstetricia Et Gynecologica Scandinavica·Liv C V ThomsenLine Bjørge
Feb 18, 2014·Cardiovascular Research·Christina W ChenS Ananth Karumanchi
Mar 13, 2014·Journal of the American College of Cardiology·Raheel AhmedVijay Kunadian
Sep 4, 2014·Journal of Obstetrics and Gynaecology Canada : JOGC = Journal D'obstétrique Et Gynécologie Du Canada : JOGC·Nir MelamedJohn C Kingdom
Sep 26, 2015·Arteriosclerosis, Thrombosis, and Vascular Biology·Line H TangeråsAnn-Charlotte Iversen
Feb 13, 2016·Acta Obstetricia Et Gynecologica Scandinavica·Fredrikke Nohr MothBjørn O Åsvold
Jun 7, 2016·American Journal of Obstetrics and Gynecology·Mary Ashley CainJudette M Louis
Mar 8, 2017·Journal of the American Heart Association·Hilde Kristin Refvik RiiseAnne Kjersti Daltveit

❮ Previous
Next ❯

Citations

May 15, 2018·Journal of the American Heart Association·Renata Cífková
Apr 26, 2019·Obstetrics and Gynecology·UNKNOWN American College of Obstetricians and Gynecologists' Presidential Task Force on Pregnancy and Heart Disease and Committee on
Jun 25, 2020·Journal of the American Heart Association·Charmaine Chu Wen LoClare Oliver-Williams
Jun 4, 2020·Acta Obstetricia Et Gynecologica Scandinavica·Heidrun Pétursdóttir MaackInger Sundström Poromaa
Aug 28, 2020·Current Hypertension Reports·Akanksha Agrawal, Nanette K Wenger
Nov 20, 2019·Current Hypertension Reports·Kathleen B MillerJill N Barnes
Oct 30, 2018·Journal of the American Heart Association·Wendy YingPamela Ouyang
May 1, 2020·Frontiers in Cardiovascular Medicine·Karen MelchiorreAsma Khalil
Jun 15, 2019·European Journal of Preventive Cardiology·Ioannis DoundoulakisGeorge Giannakoulas
Dec 2, 2020·Journal of Women's Health·Jasmina VaragicNicole Redmond
Jan 6, 2021·Environment International·Stefania PapatheodorouPetros Koutrakis
Sep 8, 2020·Birth Defects Research·Jenna B Wowdzia, Margie H Davenport
Mar 30, 2021·Hypertension·James M RobertsUNKNOWN Global Pregnancy Collaboration
Mar 30, 2021·Circulation·Nisha I ParikhUNKNOWN American Heart Association Council on Epidemiology and Prevention; Council on Arteriosclerosis, Thrombosis and Vascular Biol
Jun 10, 2021·Diabetes, Metabolic Syndrome and Obesity : Targets and Therapy·Cheng ZhouMin Jiang
Oct 16, 2020·Journal of Developmental Origins of Health and Disease·Michelle D PlummerClaire T Roberts
Aug 17, 2021·Journal of the American Heart Association·S Michelle OgunwoleWendy L Bennett
Aug 31, 2021·European Heart Journal·Frank L J VisserenUNKNOWN ESC Scientific Document Group
Sep 25, 2021·European Journal of Preventive Cardiology·Frank L J VisserenUNKNOWN ESC Scientific Document Group
Nov 16, 2021·Frontiers in Cardiovascular Medicine·Guan WangJie Du
Jan 1, 2021·Neurology·Maria C AdankSarah Schalekamp-Timmermans

❮ Previous
Next ❯

Methods Mentioned

BETA
SGA
cesarean section
cesarean sections

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.