Association between hemoglobin levels and non-alcoholic fatty liver disease in patients with young-onset type 2 diabetes mellitus.

Endocrine Journal
Qinpei DingMin Liang

Abstract

This retrospective study aimed to investigate the relationship between hemoglobin (Hb) levels and non-alcoholic fatty liver disease (NAFLD) in patients with young-onset type 2 diabetes mellitus (T2DM). Data were collected for 296 patients with young-onset T2DM admitted to the first Affiliated Hospital of Guangxi Medical University from May 2017 to January 2020. Subjects were divided into NAFLD (n = 186) and non-NAFLD groups (n = 110). Patients with NAFLD had significantly higher Hb levels (p = 0.001). According to logistic regression analysis, Hb levels were significantly correlated with NAFLD after adjusting for confounding factors [odds ratio (OR) = 1.024, 95% confidence interval = 1.003-1.046, p = 0.028]. Subjects were also grouped according to Hb quartiles. After adjusting for sex and body mass index (BMI), the OR (95%CI) for NAFLD significantly increased with increasing Hb levels (p for trend = 0.009). Patients were also divided into lean (BMI <25 kg/m2, n = 139) and overweight/obese groups (BMI ≥25 kg/m2, n = 157), with adjusted ORs (95%CI) for the highest quartiles of 1.797 (0.559-5.776) and 6.009 (1.328-27.181), respectively. Further quartile classification of Hb according to sex showed adjusted OR (95%CI) for the highe...Continue Reading

References

May 22, 2003·Diabetes Research and Clinical Practice·K M ChoiUNKNOWN Koreans-Southwest Seoul (SWS) Study
Dec 5, 2006·Nutrition·Kumiko ToshimitsuMorikazu Onji
May 20, 2008·The Anatomical Record : Advances in Integrative Anatomy and Evolutionary Biology·Geoff C FarrellR S McCuskey
Nov 19, 2008·Journal of Hepatology·Jian-Gao Fan, Geoffrey C Farrell
Sep 22, 2009·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·Jeong-Hoon LeeHyo-Suk Lee
Nov 3, 2012·Medicine·Zobair M YounossiManirath Srishord
Feb 28, 2013·Alimentary Pharmacology & Therapeutics·M D BeatonP Adams
May 30, 2013·World Journal of Gastroenterology : WJG·Wen-Shan LvMing Zheng
Jan 28, 2014·European Journal of Gastroenterology & Hepatology·Danny IssaNaim Alkhouri
Mar 19, 2014·Journal of Gastroenterology and Hepatology·Youzhao JiangBing Chen
Sep 23, 2014·The Chinese Journal of Physiology·Chyi-Huey BaiJung-Su Chang
Dec 30, 2014·Scandinavian Journal of Gastroenterology·Umit AkyuzYusuf Yilmaz
Jul 21, 2015·European Journal of Gastroenterology & Hepatology·Alpaslan Tanoglu, Muammer Kara
Dec 29, 2015·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Zobair M YounossiMark Wymer
Mar 30, 2016·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·L LiB Wang
May 24, 2016·The Journal of the American Osteopathic Association·Derrick CetinElie Nasr
Nov 5, 2016·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·Goh Eun ChungJoo Sung Kim
Jul 18, 2017·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Naga ChalasaniArun J Sanyal
Jul 25, 2017·Journal of Pediatric Gastroenterology and Nutrition·Valentina GiorgioLuca Miele
Aug 30, 2017·The Lancet. Diabetes & Endocrinology·Nadia LascarSrikanth Bellary
Dec 30, 2017·Nature Reviews. Endocrinology·Giovanni TargherChristopher D Byrne
Jun 13, 2018·Annals of Hepatology·Eva Juárez-HernándezNatalia Nuño-Lámbarri
Apr 5, 2019·Current Obesity Reports·Katherine T BrunnerMichelle T Long
Apr 24, 2019·International Journal of Molecular Sciences·Simona MarchiselloAgata Maria Rabuazzo
May 6, 2019·Primary Care Diabetes·Mohsen AfaridehAlireza Esteghamati
Aug 26, 2019·Biochimica Et Biophysica Acta. Molecular Cell Research·Dimitrios GalarisKostas Pantopoulos
Mar 12, 2020·Free Radical Biology & Medicine·Ze ChenHongliang Li
Mar 24, 2020·Nature Reviews. Endocrinology·Dianna J MaglianoJonathan E Shaw

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.