Association between hyperuricemia and atrial fibrillation in rural China: a cross-sectional study

BMC Cardiovascular Disorders
Guozhe SunYingxian Sun

Abstract

To explore the association between atrial fibrillation (AF) and serum uric acid (SUA) in a general population in rural China. From January 2013 to August 2013, we performed a cross-sectional study involving 11,956 permanent residents ≥ 35 years old in the rural Liaoning province of China. All participants completed a questionnaire, had a physical examination, and underwent an electrocardiogram (ECG) and echocardiogram. AF was diagnosed from ECG findings and/or a history of physician-confirmed AF. Blood samples were drawn for laboratory analyses and hyperuricemia was defined as an SUA level > 7.0 mg/dL in men and > 5.7 mg/dL in women, based on the NHANES-III laboratory definition. Logistic regression analyses were performed to estimate the crude and independent associations between hyperuricemia and the prevalence of AF. A total of 139 participants were diagnosed with AF, of which, 72 were self-reported, 45 were ECG-diagnosed, and 22 were both. There was a higher prevalence of AF in participants with hyperuricemia than those with normal SUA levels (2.4 vs. 1.0 %; P < 0.001). The odds ratios (OR) and 95 % confidence intervals (CI) were 2.37 (1.61-3.49) when compared to participants with normal SUA. After adjustment for other card...Continue Reading

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Citations

Oct 5, 2017·Revista da Associação Médica Brasileira·Yaniel Castro-TorresRaimundo Carmona-Puerta
Sep 21, 2018·Circulation Journal : Official Journal of the Japanese Circulation Society·Chang Hee KwonKi-Chul Sung
Nov 6, 2018·International Heart Journal·Yue ChenYunlong Xia
Apr 10, 2019·Current Pharmaceutical Design·Shuangshuang ZhangDandan Zhang
Nov 18, 2016·American Journal of Hypertension·Juha S PerkiömäkiHeikki V Huikuri

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Software Mentioned

MUSE Cardiology Information System
SPSS

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