PMID: 25726033Mar 3, 2015Paper

Association between hypoglycemia and fall-related events in type 2 diabetes mellitus: analysis of a U.S. commercial database

Journal of Managed Care & Specialty Pharmacy
Sumesh KachrooVivian Fonseca

Abstract

Hypoglycemia is a major barrier to achieving optimal glycemic control and managing diabetes successfully in patients with diabetes. Falls are the most significant consequences caused by hypoglycemia episodes. Both hypoglycemia and falls lead to substantial economic burden on the health care system in the United States. To examine the association of hypoglycemia with fall-related outcomes in elderly patients with type 2 diabetes mellitus (T2DM). Records were obtained for T2DM patients (N = 1,147,937) from January 1, 2008, to December 31, 2011. The nonhypoglycemia patients were randomly matched 1:1 by age and gender to the hypoglycemia patients. Fall-related events (composite of fall-related outcomes) were defined using ICD-9-CM codes. Conditional logistic regression models were used to compare the fall-related events within 30 days, 90 days, 180 days, and 365 days between the 2 cohorts. A total of 21,613 hypoglycemia patients were matched with 21,613 nonhypoglycemic patients. Patients with hypoglycemia had higher fall-related events within 30 days, 90 days, 180 days, and 365 days (P  less than  0.001 for all frequency differences). Conditional logistic regression analyses showed an elevated risk for fall-related events over 365 ...Continue Reading

Citations

Nov 14, 2017·Pharmacological Reports : PR·Mohammad AdilManju Sharma
Apr 9, 2015·Postgraduate Medicine·Barbara ZarowitzAndres DiGenio
Oct 23, 2015·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·Yingnan ZhaoLizheng Shi
Apr 10, 2016·The Journal of International Medical Research·Fei-Ling WuChia-Hung Lin
Aug 30, 2018·Journal of Managed Care & Specialty Pharmacy·Anthony CannonMichael Shannon
Nov 2, 2018·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·Ildiko LingvayAndreas Liebl
Aug 23, 2020·International Journal of Environmental Research and Public Health·Jieun KimSeon Heui Lee
May 11, 2016·Journal of Emergencies, Trauma, and Shock·Ayman El-MenyarHassan Al-Thani
Nov 7, 2017·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·Medha N MunshiMeenakshi Patel
Feb 23, 2021·Journal of Advanced Nursing·Ruey-Hsia WangWan-Yi Chen
Sep 1, 2021·Expert Opinion on Pharmacotherapy·Shizuka Kaneko

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