Association between interatrial block, left atrial fibrosis, and mechanical dyssynchrony: Electrocardiography-magnetic resonance imaging correlation.

Journal of Cardiovascular Electrophysiology
Luisa CiuffoHiroshi Ashikaga

Abstract

Advanced interatrial block (IAB) on a 12-lead electrocardiogram (ECG) is a predictor of stroke, incident atrial fibrillation (AF), and AF recurrence after catheter ablation. The objective of this study was to determine which features of IAB structural remodeling is associated with left atrium (LA) magnetic resonance imaging structure and function. We included 152 consecutive patients (23% nonparoxysmal AF) who underwent preprocedural ECG and cardiac magnetic resonance (CMR) in sinus rhythm before catheter ablation of AF. IAB was defined as P-wave duration ≥120 ms, and was considered partial if P-wave was positive and advanced if P-wave had a biphasic morphology in inferior leads. From cine CMR and late gadolinium enhancement, we derived LA maximum and minimum volume indices, strain, LA fibrosis, and LA dyssynchrony. A total of 77 patients (50.7% paroxysmal) had normal P-wave, 52 (34.2%) partial IAB, and 23 (15.1%) advanced IAB. Patients with advanced IAB had significantly higher LA minimum volume index (25.7 vs 19.9 mL/m2 , P = .010), more LA fibrosis (21.9% vs 13.1%, P = .020), and lower LA maximum strain rate (0.99 vs 1.18, P = .007) than those without. Advanced IAB was independently associated with LA (minimum [P = .032] and...Continue Reading

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Citations

Nov 4, 2020·Journal of the American Heart Association·Lourdes VicentUNKNOWN Baseline Interatrial Block and Transcatheter Aortic Valve Implantation (BIT) Registry Investigators †
Sep 19, 2020·The American Journal of Cardiology·Cristian HerreraUNKNOWN CAMBIAD investigators (Appendix)
Apr 20, 2021·Clinical and Experimental Hypertension : CHE·Muzaffer KahyaogluCevat Kirma
May 8, 2021·Journal of Electrocardiology·Raimundo Carmona PuertaElibet Chávez González
May 9, 2021·Annals of Noninvasive Electrocardiology : the Official Journal of the International Society for Holter and Noninvasive Electrocardiology, Inc·Fabienne KreimerMichael Gotzmann
Aug 19, 2020·International Journal of Cardiology·Manuel Martínez-SellésRoberto Elosua
Dec 5, 2021·Pacing and Clinical Electrophysiology : PACE·Ana de LeonAndres Enriquez

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