Association between intraoperative nociception and surgical invasiveness in patients undergoing non-cardiac surgery under general anesthesia: a retrospective cohort study.

Journal of Clinical Monitoring and Computing
Daisuke IshimotoMunetaka Hirose

Abstract

There are several indexes of intraoperative nociception during surgery under general anesthesia. Although a higher degree of surgical invasiveness increases intraoperative nociception, an association between the index of intraoperative nociception and severity of surgical invasiveness has not been reported. We hypothesized that there is associations between averaged values of nociceptive response (NR) throughout surgery (mean NR), as the index of intraoperative nociception, and surgical severity codes in the Surgical outcome risk tool (SORT) or procedure risk codes in the Surgical mortality probability model (S-MPM). The primary outcome was the association between mean NR and severity scores of surgical procedure. Hence, a single institutional retrospective cohort study was performed in consecutive patients undergoing non-cardiac surgery under general anesthesia from June 2018 to May 2019. There were significant increases in the three categories of procedure risk in the S-MPM corresponding to the increase in mean NR values in 5090 patients. In the SORT, the highest intensity in the four categories of surgical severity also significantly correlated with the increase in mean NR values. Increasing intensity of intraoperative nocic...Continue Reading

References

Nov 13, 2014·The British Journal of Surgery·K L ProtopapaS R Moonesinghe
May 21, 2018·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Munetaka HiroseTsuneo Tatara
Apr 29, 2019·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Hiroki MiyawakiMunetaka Hirose
May 3, 2019·British Journal of Anaesthesia·Thomas Ledowski

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