PMID: 15328740Aug 27, 2004Paper

Association between Key-Gaskell syndrome and infection by Clostridium botulinum type C/D

The Veterinary Record
F NunnI R Poxton

Abstract

There is growing evidence that equine dysautonomia is a toxicoinfection with Clostridium botulinum type C. The possibility that feline dysautonomia has the same aetiology was investigated by attempting to detect botulinum type C neurotoxin in the food, faeces and the contents of the ileum of affected cats, and by serology. The toxin was detected directly in four of eight affected cats and after enrichment in seven of them, and in their dried food. No toxin was detected in healthy control cats or in their tinned food. Recent exposure to the organism was assessed by the detection of immunoglobulin A (IgA) in the faeces of healthy control cats and affected cats. The levels of IgA antibodies to the toxin and to surface antigens of C. botulinum type C in the faeces of the affected cats 14 weeks after the outbreak were significantly higher than in the faeces of the control cats.

References

Apr 27, 1991·The Veterinary Record·K E Whitwell
Feb 13, 1982·The Veterinary Record·T J Key, C J Gaskell
Feb 12, 2000·Journal of Immunological Methods·C BergquistA Svennerholm
Apr 9, 2001·The Veterinary Record·M H MilneJ L Fitzpatrick
May 2, 2001·Journal of the American Veterinary Medical Association·R D BerghausJ G Thorne
Nov 7, 2002·Journal of the American Veterinary Medical Association·Kenneth R HarkinJerome C Nietfeld
Jan 30, 2004·Veterinary Parasitology·Arnaud Delafosse, Abdesalam Adoum Doutoum

❮ Previous
Next ❯

Citations

Oct 24, 2007·Journal of Feline Medicine and Surgery·Aimee C KidderThomas Schermerhorn
May 11, 2010·Journal of Feline Medicine and Surgery·Rosa NovellasGawain J C Hammond
Apr 12, 2007·The Journal of Small Animal Practice·S J M NiessenG B Cherubini
Mar 24, 2017·PloS One·Bruce C McGorumR Scott Pirie
Mar 4, 2014·Equine Veterinary Journal·R S PirieN P H Hudson
Apr 8, 2020·The Veterinary Record·Katherine Elizabeth ClarkeDanielle Gunn-Moore
Apr 1, 2008·The Veterinary Record·G T Edwards, A Nevel

❮ Previous
Next ❯

Related Concepts

Related Feeds

Botulism (ASM)

Botulism is a rare but serious paralytic illness caused by a nerve toxin that is produced by the bacterium clostridium botulinum. Discover the latest research on botulism here.

Botulism

Botulism is a rare but serious paralytic illness caused by a nerve toxin that is produced by the bacterium clostridium botulinum. Discover the latest research on botulism here.

Related Papers

Journal of Comparative Pathology
M Pollin, I R Griffiths
Journal of Veterinary Internal Medicine
R C LongshoreR A Kroll
The Veterinary Record
A T Edney, C J Gaskell
© 2021 Meta ULC. All rights reserved