Association between lumbar bone mineral density and serum uric acid in postmenopausal women: a cross-sectional study of healthy Chinese population

Archives of Osteoporosis
Wen HanXiang-Mei Chen

Abstract

Partial correlation and regression analyses were used in this study. We showed that there is a linear relationship between bone mineral density and serum uric acid within the normal physiologic range, and higher serum uric acid levels had a protective effect on bone loss in postmenopausal osteoporosis. The significance of the relationship between lumbar bone mineral density (BMD) and serum uric acid (SUA) levels is unclear. The aims of this study were to investigate on a population-level the association between lumbar BMD and SUA within the normal physiologic range and to determine whether SUA plays a protective role in bone loss in healthy postmenopausal Chinese women. This was a community-based cross-sectional study involving 390 healthy postmenopausal women, 47-89 years of age, conducted in Shenyang, China. The BMD was measured at the lumbar spine using dual-energy X-ray absorptiometry (DXA). The SUA levels were obtained at each DXA visit. Partial correlation and regression analyses were applied to determine the associations. The SUA levels were significantly different between the normal BMD, osteopenia, and osteoporosis groups. The lumbar BMD was positively correlated with SUA in postmenopausal women after adjustment for ag...Continue Reading

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Citations

Dec 6, 2018·Menopause : the Journal of the North American Menopause Society·Wen HanXiang-Mei Chen
Jul 18, 2020·International Journal of Endocrinology·Xiaocong YaoZhongxin Zhu
Aug 14, 2018·European Journal of Clinical Investigation·Christopher AdlbrechtAlberto Bouzas-Mosquera
Jun 30, 2018·International Orthopaedics·Yanmao WangYimin Chai
Dec 20, 2017·Menopause : the Journal of the North American Menopause Society·Wen HanXiang-Mei Chen
Jan 9, 2021·Journal of Bone and Mineral Metabolism·Hang ZhaoYong Tang
Apr 20, 2021·Frontiers in Endocrinology·Wisam Nabeel IbrahimMarawan Abdelhamid Abu-Madi
Jun 10, 2021·Scientific Reports·Jung Woo LeeHyo Geun Choi
Jun 11, 2021·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·Tomaz KocjanBarbara Ostanek

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