Abstract
The previous studies on the association between marital status and stroke outcomes were rare. Furthermore, the existing studies mostly focused on the protective effect of marriage on survival. We conducted the study to evaluate the association between marital status and adverse stroke outcomes in patients with AIS based on China national stroke registry. This was a multicenter, prospective cohort study of patients with AIS. Patients were classified into two groups based on marital status at admission: married and unmarried. The primary outcomes included all-cause mortality, stroke recurrence, combined endpoint, and stroke disability. Stroke disability was defined as modified Rankin Scale of 2-6. Of 12,118 patients, 1220 were unmarried and 10,898 married. Unmarried patients had higher proportion of 1-year post-stroke events than married patients did. As compared with being unmarried, the adjusted odds ratios with 95% confidence interval of being married for outcomes were as follows: 0.70 (0.58-0.84) for all-cause mortality, 0.78 (0.66-0.91) for stroke recurrence, 0.77 (0.66-0.90) for combined endpoint, and 0.75 (0.65-0.88) for stroke disability. Interactions between marital status and education were significant for all outcomes ...Continue Reading
References
Jun 16, 2005·Neurology·B Boden-AlbalaR L Sacco
Oct 3, 2006·Social Science & Medicine·Lamberto ManzoliAntonio Boccia
Jun 9, 2009·Social Science & Medicine·Gerard John MolloyMark Hamer
May 26, 2011·International Journal of Stroke : Official Journal of the International Stroke Society·Yongjun WangUNKNOWN China National Stroke Registry Investigators
Jul 12, 2011·Psychoneuroendocrinology·S HäfnerUNKNOWN MONICA/KORA Study Investigators
Nov 5, 2011·Stroke; a Journal of Cerebral Circulation·Liping LiuYongjun Wang
Jan 23, 2014·Lancet·Valery L FeiginUNKNOWN Global Burden of Diseases, Injuries, and Risk Factors Study 2010 (GBD 2010) and the GBD Stroke Experts Group
Mar 13, 2014·BMC Medicine·Sarah FloudUNKNOWN Million Women Study Collaborators
Apr 22, 2014·Metabolic Brain Disease·Venugopal Reddy Venna, Louise D McCullough
Aug 21, 2014·Stroke; a Journal of Cerebral Circulation·Mathew J ReevesMoira K Kapral
Oct 9, 2014·Stroke; a Journal of Cerebral Circulation·Klaus Kaae AndersenTom Skyhøj Olsen
Apr 16, 2015·Circulation. Cardiovascular Quality and Outcomes·Matthew E DupreEric D Peterson
Sep 1, 2015·Lancet·Christopher J L MurrayTheo Vos
Jul 15, 2016·BMC Neurology·Petra RedforsChristina Jern
Oct 26, 2016·Stroke; a Journal of Cerebral Circulation·Yuesong PanYongjun Wang
Dec 16, 2016·Journal of the American Heart Association·Matthew E Dupre, Renato D Lopes
May 4, 2017·Stroke; a Journal of Cerebral Circulation·Johanna PennlertMarie Eriksson
Citations
Jul 16, 2019·Journal of the American Heart Association·Katrine Damgaard SkyrudJon Helgeland
Oct 10, 2020·BMC Cardiovascular Disorders·Gertrude NamaleRobert Newton
Apr 4, 2021·Healthcare·Stefania LarattaAntonio Cerasa
Oct 20, 2019·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Yuan XuYingping Yi
Oct 6, 2021·Scandinavian Journal of Public Health·Elina EiniöPekka Martikainen