Association between marriage and outcomes in patients with acute ischemic stroke

Journal of Neurology
Qi LiuYongjun Wang

Abstract

The previous studies on the association between marital status and stroke outcomes were rare. Furthermore, the existing studies mostly focused on the protective effect of marriage on survival. We conducted the study to evaluate the association between marital status and adverse stroke outcomes in patients with AIS based on China national stroke registry. This was a multicenter, prospective cohort study of patients with AIS. Patients were classified into two groups based on marital status at admission: married and unmarried. The primary outcomes included all-cause mortality, stroke recurrence, combined endpoint, and stroke disability. Stroke disability was defined as modified Rankin Scale of 2-6. Of 12,118 patients, 1220 were unmarried and 10,898 married. Unmarried patients had higher proportion of 1-year post-stroke events than married patients did. As compared with being unmarried, the adjusted odds ratios with 95% confidence interval of being married for outcomes were as follows: 0.70 (0.58-0.84) for all-cause mortality, 0.78 (0.66-0.91) for stroke recurrence, 0.77 (0.66-0.90) for combined endpoint, and 0.75 (0.65-0.88) for stroke disability. Interactions between marital status and education were significant for all outcomes ...Continue Reading

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Citations

Jul 16, 2019·Journal of the American Heart Association·Katrine Damgaard SkyrudJon Helgeland
Oct 20, 2019·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Yuan XuYingping Yi
Oct 6, 2021·Scandinavian Journal of Public Health·Elina EiniöPekka Martikainen

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