Association between Maternal Smoking during Pregnancy and Low Birthweight: Effects by Maternal Age

PloS One
Wei ZhengOkinawa Child Health Study Group

Abstract

Maternal smoking during pregnancy has been consistently related to low birthweight. However, older mothers, who are already at risk of giving birth to low birthweight infants, might be even more susceptible to the effects of maternal smoking. Therefore, this study aimed to examine the modified association between maternal smoking and low birthweight by maternal age. Data were obtained from a questionnaire survey of all mothers of children born between 2004 and 2010 in Okinawa, Japan who underwent medical check-ups at age 3 months. Variables assessed were maternal smoking during pregnancy, maternal age, gestational age, parity, birth year, and complications during pregnancy. Stratified analyses were performed using a logistic regression model. In total, 92641 participants provided complete information on all variables. Over the 7 years studied, the proportion of mothers smoking during pregnancy decreased from 10.6% to 5.0%, while the prevalence of low birthweight did not change remarkably (around 10%). Maternal smoking was significantly associated with low birthweight in all age groups. The strength of the association increased with maternal age, both in crude and adjusted models. Consistent with previous studies conducted in We...Continue Reading

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Citations

Sep 29, 2017·Healthcare·Malshani L PathirathnaChandraratne M B Dematawewa
May 10, 2018·Obstetrics and Gynecology·Alaina M BeverKatherine L Grantz
Jun 25, 2019·Psychology, Health & Medicine·Catarina Tojal, Raquel Costa
Apr 4, 2021·Nutrients·Maria Teresa Murillo-LlorenteMarcelino Pérez-Bermejo
Jan 22, 2021·Public Health Nutrition·Sorayya Kheirouri, Mohammad Alizadeh
Jul 15, 2021·Experimental and Therapeutic Medicine·Litzy Gisella BermudezAdriana Rojas

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