Association between muscle function, cognitive state, depression symptoms and quality of life of older people: evidence from clinical practice

Aging Clinical and Experimental Research
Salah Gariballa, Awad Alessa

Abstract

Although low muscle function/strength is an important predictor of poor clinical outcome in older patients, information on its impact on mental health in clinical practice is still lacking. The aim of this report is to measure the impact of low muscle function measured by handgrip strength on mental health of older people during both acute illness and recovery. Four hundred and thirty-two randomly selected hospitalized older patients had their baseline demographic and clinical characteristics assessed within 72 h of admission, at 6 weeks and at 6 months. Low muscle strength-handgrip was defined using the European Working Group criteria. Mental health outcome measures including cognitive state, depression symptoms and quality of life were also measured. Among the 432 patients recruited, 308 (79%) had low muscle strength at baseline. Corresponding figures at 6 weeks and at 6 months were 140 (73%) and 158 (75%). Patients with poor muscle strength were significantly older with increased disability and poor nutritional status compared with those with normal muscle strength. After adjustment for age, gender, disability, comorbidity including severity of acute illness and body mass index patients with low muscle strength had worse cog...Continue Reading

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Citations

Jul 28, 2017·Expert Review of Pharmacoeconomics & Outcomes Research·Charlotte BeaudartOlivier Bruyère
Nov 6, 2018·Journal of Clinical Medicine·Dong Hyun YoonWook Song
Sep 24, 2020·International Journal of Environmental Research and Public Health·Jae-Moo Lee, Edward J Ryan
Apr 10, 2019·Wiener klinische Wochenschrift·Konstantinos VolaklisJacob Linseisen
May 12, 2021·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Xiuxia HuangGuang Hao

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