Association Between Muscle Wasting and Muscle Strength in Patients Who Developed Severe Sepsis And Septic Shock

Shock
Rodrigo Cerqueira Borges, Francisco Garcia Soriano

Abstract

To evaluate the association between the rectus femoris cross-sectional area (RFCSA) and the muscular strength obtained at the bedside in patients forwarded to the intensive care unit (ICU) for severe sepsis and septic shock. An observational study of prospective cohort. RFCSA was assessed by ultrasound on the following day of the ICU admission and monitored during hospitalization. The patients performed clinical tests of muscle strength (Medical Research Council (MRC) scale and handgrip dynamometry), when they could understand the verbal commands of the examiners. In 37 patients hospitalized for sepsis there was a significant decline in RFCSA of 5.18 (4.49-5.96) cm on the 2nd day of ICU for 4.37 (3.71-5.02) cm at hospital discharge. Differently, the handgrip strength showed an increase from the awakening of 12.00 (7.00-20.00) Kgf to 19.00 (14.00-26.00) Kgf until hospital discharge. Patients in mechanical ventilation had a greater tendency to decline in the RFCSA compared with patients who did not receive mechanical ventilation, however without being significant (P = 0.08). There was a negative association between RFCSA delta (2nd day of ICU-ICU discharge) and handgrip strength (r = 0.51, P < 0.05), and a male and Sepsis-related...Continue Reading

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Citations

Nov 27, 2018·Shock·Hongkuan Fan, Andrew J Goodwin
Feb 6, 2021·Romanian Journal of Internal Medicine = Revue Roumaine De Médecine Interne·Eleousa OikonomouDimitris Velissaris
Apr 24, 2021·Critical Care : the Official Journal of the Critical Care Forum·Djahid KennoucheJulien Gondin

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