Association Between Neurocognitive Decline and Visual Field Variability in Glaucoma

JAMA Ophthalmology
Alberto Diniz-FilhoFelipe A Medeiros

Abstract

Visual field variability may impair detection of glaucoma progression over time. Despite the possible overlap between neurocognitive disorders and glaucoma in older individuals, no study has investigated the association between cognitive changes and visual field variability. To evaluate the association between global neurocognitive impairment and visual field variability in patients diagnosed as having glaucoma or glaucoma suspects. This prospective observational cohort study was conducted at the Visual Performance Laboratory, University of California, San Diego. The study involved 211 eyes of 115 patients followed up for a mean (SD) period of 2.5 (0.8) years, ranging from 1.2 to 4.7 years. Data were obtained during the period extending from March 2011 to April 2015, with data analysis conducted from November 2015 to May 2016. Association between cognitive decline and visual field variability. Patients were monitored with standard automated perimetry (SAP) and had longitudinal assessment of cognitive ability using the Montreal Cognitive Assessment (MoCA). Visual field variability was estimated by the SD of the residuals of ordinary least squares linear regressions of SAP mean deviation (MD) values over time. Linear regression m...Continue Reading

Citations

Apr 30, 2019·Journal of Glaucoma·Pushpa RamanKhairul H Mohd Khalid
Jan 3, 2020·Current Opinion in Ophthalmology·Sophia Y Wang, Kuldev Singh
Mar 20, 2020·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·Samantha Sze-Yee LeeAlexander A Black
Dec 20, 2017·Current Opinion in Ophthalmology·Zhichao Wu, Felipe A Medeiros
Sep 16, 2017·Frontiers in Aging Neuroscience·Viswa GangeddulaHannes Devos
Dec 7, 2018·Translational Vision Science & Technology·Joseph CaprioliKouros Nouri-Mahdavi
Oct 23, 2019·Translational Vision Science & Technology·Alessandro RabioloJoseph Caprioli
Oct 1, 2020·Journal of Clinical Medicine·Carlo NucciNicola Toschi
Dec 31, 2019·Journal of Ophthalmology·Maria Emília V GuimarãesTiago S Prata
Sep 15, 2020·Journal of Glaucoma·Natasha N KolomeyerJoseph F Panarelli
Dec 15, 2020·Ophthalmology. Glaucoma·Eun Young ChoiMengyu Wang
Nov 18, 2020·Translational Vision Science & Technology·Christopher Jong, Simon Edward Skalicky
May 15, 2021·The British Journal of Ophthalmology·Brian StaggFelipe A Medeiros
Jan 19, 2020·Ophthalmology·Alessandro RabioloJoseph Caprioli

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