Association between non-alcoholic fatty liver disease and obstructive sleep apnea.

World Journal of Gastroenterology : WJG
Ilaria UmbroMaria Del Ben

Abstract

Non-alcoholic fatty liver disease (NAFLD) is an emerging liver disease and currently the most common cause of incidental abnormal liver tests. The pathogenesis of NAFLD is multifactorial and many mechanisms that cause fatty liver infiltration, inflammation, oxidative stress and progressive fibrosis have been proposed. Obstructive sleep apnea (OSA) may be linked with the pathogenesis and the severity of NAFLD. To study the association between NAFLD and OSA considering also the efficacy of continuous positive airway pressure (CPAP) treatment. A PubMed search was conducted using the terms "non-alcoholic fatty liver disease AND (obstructive sleep apnea OR obstructive sleep disorders OR sleep apnea)". Research was limited to title/abstract of articles published in English in the last 5 years; animal and child studies, case reports, commentaries, letters, editorials and meeting abstracts were not considered. Data were extracted on a standardized data collection table which included: First author, publication year, country, study design, number of patients involved, diagnosis and severity of OSA, diagnosis of NAFLD, patient characteristics, results of the study. In total, 132 articles were initially retrieved on PubMed search and 77 i...Continue Reading

References

Apr 29, 1993·The New England Journal of Medicine·T YoungS Badr
Apr 18, 1998·Gastroenterology·C P Day, O F James
Mar 17, 2000·The Journal of Clinical Endocrinology and Metabolism·A N VgontzasG P Chrousos
Mar 5, 2002·American Journal of Respiratory and Critical Care Medicine·Mary S M IpKaren S L Lam
Apr 19, 2002·The New England Journal of Medicine·Paul Angulo
Apr 19, 2003·Journal of Gastroenterology and Hepatology·Francesco AngelicoCesare Alessandri
Apr 30, 2003·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Brent A Neuschwander-Tetri, Stephen H Caldwell
Sep 9, 2004·American Journal of Epidemiology·Naresh M PunjabiUNKNOWN Sleep Heart Health Study Investigators
Dec 16, 2004·The Journal of Clinical Endocrinology and Metabolism·F AngelicoF Violi
Mar 30, 2007·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Vladimir SavranskyVsevolod Y Polotsky
Apr 7, 2009·Metabolic Syndrome and Related Disorders·Andrew D CalvinVirend K Somers
May 13, 2010·Digestive Diseases·Stephen Caldwell, Curtis Argo
Jan 25, 2012·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Donghee KimW Ray Kim
Jun 19, 2013·Journal of the American College of Cardiology·Luciano F DragerGeraldo Lorenzi-Filho
Jun 9, 2015·World Journal of Hepatology·Licia PolimeniFrancesco Angelico
Jul 16, 2015·Sleep & Breathing = Schlaf & Atmung·Jia-Chao QiXiao Chen
Sep 20, 2015·Ultrasound in Medicine & Biology·Maria ButtacavoliMaria R Bonsignore
Feb 20, 2016·European Journal of Gastroenterology & Hepatology·Xiao ChenJian-Ming Zhao
Mar 20, 2016·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Ahmet ArısoyMahfuz Turan
Nov 5, 2016·Sleep Medicine·Mako NagayoshiPamela L Lutsey
Feb 7, 2017·Journal of Clinical Sleep Medicine : JCSM : Official Publication of the American Academy of Sleep Medicine·Vishesh K KapurChristopher G Harrod
Nov 23, 2017·The New England Journal of Medicine·Anna M Diehl, Christopher Day
Dec 11, 2017·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Li-Da ChenLi Lin
May 23, 2018·Endocrinology·Min LiYan Lu
Jun 9, 2018·The European Respiratory Journal·Wojciech TrzepizurUNKNOWN on the behalf of the METABOL group
Aug 11, 2018·Journal of Clinical Sleep Medicine : JCSM : Official Publication of the American Academy of Sleep Medicine·Donghee KimClete Kushida
Dec 31, 2019·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Francesco BarattaMaria Del Ben
Jan 20, 2020·Current Cardiology Reports·Liann Abu SalmanJordana B Cohen

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Citations

Dec 16, 2020·Clinical and Molecular Hepatology·Karn WijarnpreechaDonghee Kim

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Methods Mentioned

BETA
biopsy

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