Association between nutritional blood-based biomarkers and clinical outcome in sarcopenia patients

Clinical Nutrition ESPEN
Salah Gariballa, Awad Alessa

Abstract

Although several micronutrients deficiency were reported to be associated with poor muscle function, however information on sarcopenia patients is still lacking. The aim of this report was to measure some micronutrients blood-based status in sarcopenia patients during both acute illness and recovery. We assessed nutritional status of randomly selected hospitalised patients using anthropometric, haematological and biochemical data at baseline, 6 weeks and at 6 months. Sarcopenia was diagnosed from low muscle mass and low muscle strength using anthropometric measures based on the European Working Group criteria. Micronutrient status was compared between sarcopenia patients and those without sarcopenia over a 6 months period. Forty-four out of 432 patients (10%) were diagnosed with sarcopenia on admission. Patients diagnosed with sarcopenia had lower micronutrients concentrations compared to those patients without sarcopenia however, the results were statistically significant only for baseline serum albumin, red cell folate and plasma zinc (p < 0.05). Lycopene, retinol, red cell folate and zinc were also significantly lower in sarcopenia patients at 6 weeks. Sarcopenia patients readmitted to hospital had poor baseline micronutrien...Continue Reading

Citations

Mar 20, 2020·Journal of Cachexia, Sarcopenia and Muscle·Kota TsutsumimotoHiroyuki Shimada
Sep 25, 2021·Biomédica : revista del Instituto Nacional de Salud·Jack Roberto Silva-FhonRosalina Aparecida Partezani-Rodrigues

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