Association between organophosphate pesticides exposure and thyroid hormones in floriculture workers

Toxicology and Applied Pharmacology
Marina LacasañaMariano E Cebrián

Abstract

The ability of organophosphate pesticides to disturb thyroid gland function has been demonstrated by experimental studies on animal, but evidence of such effects on human remains scarce. The aim of this study was to assess the association between exposure to organophosphate compounds and serum levels of thyroid hormones in floriculture workers. A longitudinal study was conducted on 136 male subjects from the State of Mexico and Morelos, Mexico, occupationally exposed to organophosphate pesticides, during agricultural periods of high (rainy season) and low (dry season) levels of pesticide application. Using a structured questionnaire, a survey was carried out on sociodemographic characteristics, anthropometry, clinical history, alcohol and tobacco consumption, residential chemical exposure, and occupational history. Urine and blood samples were taken the day after pesticide application to determine urine dialkylphosphate (DAP) levels, serum levels of TSH, total T(3), total T(4), serum PON1 activity, and serum p,p'-DEE levels. The analysis of the association between DAP levels and thyroid hormonal profile was carried out using multivariate generalized estimating equation (GEE) models. Our results showed an increase in both TSH an...Continue Reading

References

Sep 1, 1996·Journal of Applied Toxicology : JAT·N AkhtarM Shahab
Feb 24, 2001·Human & Experimental Toxicology·S S ZaidiH N Saiyed
Mar 30, 2002·Cadernos de saúde pública·Marcia Galván-PortilloLizbeth López-Carrillo
Aug 23, 2002·Toxicology Letters·J CockerK Jones
May 31, 2003·Journal of Toxicology and Environmental Health. Part a·Vincent F GarryBarbara L Burroughs
Dec 3, 2003·Environmental Research·Leticia YáñezFernando Díaz-Barriga
Feb 3, 2004·Environmental Health Perspectives·Dana B BarrLarry L Needham
Sep 2, 2004·Journal of Exposure Analysis and Environmental Epidemiology·John D MeekerRuss Hauser
Jan 18, 2005·Clinica Chimica Acta; International Journal of Clinical Chemistry·Lucio G CostaClement E Furlong
Jan 27, 2005·Biochemical Pharmacology·Lucio G CostaClement E Furlong
Sep 6, 2005·Environmental Health Perspectives·Rogelio RecioMariano E Cebrián
Sep 29, 2005·Journal of Toxicology and Environmental Health. Part B, Critical Reviews·G BouvierI Momas
Jan 24, 2006·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Jun UeyamaKenzo Takagi
Feb 24, 2006·Pharmacogenetics and Genomics·Clement E FurlongBrenda Eskenazi
Apr 29, 2006·European Journal of Endocrinology·Malene BoasKatharina M Main
Jun 1, 2006·Journal of Exposure Science & Environmental Epidemiology·Asa BradmanBrenda Eskenazi
Jun 30, 2006·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·R Orie BrowneAlon Friedman
Dec 7, 2006·Environmental Health : a Global Access Science Source·Gunnar ToftJens Peter Bonde
Apr 14, 2007·Environmental Health Perspectives·Luisa Torres-SánchezLizbeth López-Carrillo
Apr 18, 2007·Journal of Applied Toxicology : JAT·Antonio Barraza-VázquezRogelio Recio-Vega
Aug 30, 2008·Critical Reviews in Toxicology·David L EatonPeter S Spencer
Oct 24, 2008·Environmental Health : a Global Access Science Source·Marina Bjørling-PoulsenPhilippe Grandjean
Dec 17, 2008·Toxicology and Applied Pharmacology·Rebecca J RichterClement E Furlong
Dec 19, 2008·Chemosphere·Antonio Trejo-AcevedoIván N Pérez-Maldonado
Jan 31, 2009·Endocrinology·Maria Izabel Chiamolera, Fredric E Wondisford

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Citations

May 11, 2011·International Journal of Environmental Research and Public Health·Ilona Silins, Johan Högberg
Sep 13, 2011·International Journal of Environmental Research and Public Health·Mary N ArmesBeate Ritz
Dec 4, 2015·Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals·Fatima Zohra MadaniMichel Narce
Jan 29, 2013·Toxicology·Elena VakonakiDemetrios A Spandidos
Nov 1, 2015·Environmental Research·Zaida I FigueroaMelissa J Perry
Jun 22, 2011·American Journal of Industrial Medicine·Anna LeaveyIgor Burstyn
Jul 8, 2015·Occupational and Environmental Medicine·Catherine C LerroLaura E Beane Freeman
Aug 7, 2012·Inhalation Toxicology·Manuela CiarroccaAngela Sancini
Jul 6, 2014·Environmental Research·Basem ShomarJerome Nriagu
Jun 7, 2016·International Journal of Hygiene and Environmental Health·Élida Campos, Carmen Freire
Jun 28, 2016·Environmental Research·Julia Blanco-MuñozClemente Aguilar-Garduño
Oct 21, 2016·Environmental Research·Camila PiccoliCarmen Freire
Nov 8, 2016·Journal of Occupational and Environmental Medicine·Thomas A ArcurySara A Quandt
Mar 6, 2013·Asia-Pacific Journal of Public Health·Dilshad A KhanHizbullah Khan
Jul 12, 2018·The International Journal of Occupational and Environmental Medicine·Suhartono SuhartonoMateus Sakundarno
Sep 27, 2018·Environmental Health Perspectives·Srishti ShresthaDale P Sandler
Feb 28, 2018·International Journal of Occupational and Environmental Health·Clemente Aguilar-GarduñoMarina Lacasaña
Sep 26, 2013·Journal of Occupational and Environmental Medicine·Whitney S GoldnerTricia D LeVan
Dec 21, 2018·Revista de salud pública·Ángela L LondoñoPatricia Landázuri
Aug 1, 2019·International Journal of Environmental Research and Public Health·Pornpimol KongtipSusan Woskie
Feb 23, 2020·Military Medicine·Jennifer TherkornKaitlin Rainwater-Lovett
Sep 27, 2016·International Journal of Environmental Research and Public Health·Khaoula ToumiBruno Schiffers
Nov 26, 2020·Journal of Occupational and Environmental Hygiene·Yonatal Mesfin TeferaDino Pisaniello
Jan 24, 2021·The Science of the Total Environment·Beatriz SuárezCarmen Freire
Jan 23, 2021·Toxics·Pornpimol KongtipSusan Woskie
Oct 31, 2020·International Journal of Environmental Research and Public Health·Neeranuch SuwannarinShoji F Nakayama
Feb 14, 2021·International Journal of Hygiene and Environmental Health·Simone PhillipsJose Ricardo Suarez-Lopez
Nov 27, 2018·Chemosphere·Tanandra BernieriLuciano Basso da Silva
Jun 3, 2021·International Journal of Environmental Research and Public Health·Neeranuch SuwannarinShoji F Nakayama

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