Association Between Passive Smoking and the Risk of Cervical Intraepithelial Neoplasia 1 in Korean Women

Journal of Epidemiology
Kyung-Jin MinMi Kyung Kim

Abstract

The role of passive smoking on cervical carcinogenesis remains controversial. We investigated the association of passive smoking with the risk of cervical intraepithelial neoplasia (CIN) and cervical cancer. The study recruited 1,322 women, aged 18-65 with normal cytology (n = 592), CIN1 (n = 420), CIN2/3 (n = 165), and cervical cancer (n = 145) from 2006 to 2009. This study is a cross-sectional analysis using the baseline data from the Korean human papillomavirus (HPV) cohort study. Detailed information on smoking behaviors and lifestyles were collected using questionnaires. Multinomial logistic regression analysis was performed to estimate multivariable-adjusted odds ratios (ORs). Passive smoking was not statistically related to the risk of CINs and cervical cancer. However, passive smoking among non-smokers was associated with higher CIN 1 risk (OR 1.53; 95% confidence interval [CI], 1.07-2.18), compared to not passive smoking, after adjusting for demographic factors, lifestyles, and oncogenic-HPV infection status. CIN 1 risk increased with longer time exposed to passive smoking (P for trend <0.0003). Multivariate odds of <2 hours/day of passive smoking and that of ≥2 hours/day of passive smoking were 2.48 (95% CI, 1.49-4.14...Continue Reading

References

Mar 17, 1989·JAMA : the Journal of the American Medical Association·M L SlatteryJ W Gardner
Sep 1, 1996·Japanese Journal of Cancer Research : Gann·K HiroseS Tokudome
Dec 22, 1999·International Journal of Epidemiology·S H JeeI S Kim
Apr 23, 2002·JAMA : the Journal of the American Medical Association·Diane SolomonUNKNOWN Bethesda 2001 Workshop
Jul 10, 2002·Cancer Detection and Prevention·Ann L CokerLucia Pirisi
Mar 30, 2004·Gynecologic Oncology·Sun-Kuie Tay, Kae-Jack Tay
Dec 31, 2004·Obstetrics and Gynecology·Cornelia L TrimbleAnthony J Alberg
Oct 6, 2005·International Journal of Cancer. Journal International Du Cancer·UNKNOWN International Collaboration of Epidemiological Studies of Cervical CancerS Sweetland
Sep 5, 2006·Vaccine·Anna-Barbara MoscickiLuisa L Villa
Mar 5, 2008·International Journal of Epidemiology·Salvatore VaccarellaUNKNOWN IARC HPV Prevalence Surveys (IHPS) Study Group
Feb 5, 2010·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Marko MimicaLidija Pejković
Jul 16, 2010·Cancer Science·Koji MatsumotoUNKNOWN Japan HPV And Cervical Cancer (JHACC) Study Group
Jan 21, 2011·American Journal of Obstetrics and Gynecology·Kristy K WardCarmen Radecki Breitkopf
May 26, 2011·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Karly S LouieUNKNOWN International Agency for Research on Cancer Multicenter Cervical Cancer Study Group
Apr 26, 2012·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·K H KimK Lee
Jan 16, 2013·Asian Pacific Journal of Cancer Prevention : APJCP·Sitakan NatphopsukTakafumi Ishida
Apr 4, 2013·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Mark Schiffman, Nicolas Wentzensen
Sep 5, 2014·Epidemiology and Infection·H Y OhS Park
Nov 1, 2006·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Thomas C Wright

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