Association between pneumococcal pneumonia and venous thromboembolism in hospitalized patients: A nationwide population-based study

Respirology : Official Journal of the Asian Pacific Society of Respirology
Yu-Guang ChenChia-Hung Kao

Abstract

This was a nationwide population-based retrospective cohort study to investigate the risk of developing deep-vein thrombosis (DVT) and pulmonary embolism (PE) in patients with a pneumococcal pneumonia. We analysed data from 1998 to 2010 from the Taiwan National Health Insurance Database. The follow-up period was extended to the end of 2011. We identified patients with pneumococcal pneumonia and selected a comparison cohort matched for age, sex and diagnosis year at a ratio of one pneumococcal pneumonia patient to four control patients. We analysed the risks of DVT and PE by using Cox proportional hazards regression models, including gender, age and comorbidities. In total, 18,928 pneumococcal pneumonia patients and 75,712 controls were included in the study. The risks of developing DVT and PE were 1.78-fold (95% CI: 1.39-2.28) and 1.97-fold (95% CI: 1.43-2.72), respectively, in patients with pneumococcal pneumonia compared to the control cohort after adjusting for age, gender and comorbidities. The increased risks of DVT and PE were significant in patients who exhibited any comorbidity. The incidences of DVT and PE were highest in the first 4 weeks after pneumonia and remained slightly elevated from 13 weeks to 2 years after ac...Continue Reading

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Citations

Feb 27, 2016·Respirology : Official Journal of the Asian Pacific Society of Respirology·Helen E JoClaire Wainwright
Apr 29, 2015·Respirology : Official Journal of the Asian Pacific Society of Respirology·Lutz Beckert, Anthony Rahman
Jul 1, 2015·Journal of Thrombosis and Thrombolysis·Stefania FrassonUNKNOWN RIETE Investigators
Jul 23, 2020·Clinical Medicine : Journal of the Royal College of Physicians of London·Eleni E LadikouTimothy Chevassut
Apr 21, 2017·Canadian Respiratory Journal : Journal of the Canadian Thoracic Society·T J MarrieDean T Eurich
Jan 16, 2021·Aging Clinical and Experimental Research·Michele CorrealeNatale Daniele Brunetti
Oct 11, 2017·The American Journal of Medicine·Kevin P CohoonJohn A Heit
Feb 28, 2021·International Journal of Clinical Practice·Shih-Ting HuangChia-Hung Kao
Mar 4, 2021·Clínica e investigación en ginecología y obstetricia·N Martínez-SánchezJ L Bartha

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