Jul 18, 2014

Association between resting energy expenditure, psychopathology and HPA-axis in eating disorders

World Journal of Clinical Cases
Giovanni CastelliniValdo Ricca


To investigate the complex relationships between resting energy expenditure (REE), eating psychopathology, and Hypothalamus Pituitary Adrenal axis functioning in patients with eating disorders. The study was designed as a cross-sectional survey, and it was planned by the Clinic for Eating Disorders of the University of Florence (Italy). The protocol was approved by the Ethics Committee of the Institution. Twenty two anorexia nervosa and twenty one Bulimia Nervosa patients were assessed by means of a clinical interview and the structured clinical interview for diagnostic and statistical manual of mental disorders, fourth edition. Eating attitudes and behaviour were specifically investigated by means of the eating disorder examination questionnaire (EDE-Q). Patients were also evaluated by means of the symptom checklist (SCL 90-R), REE was measured by means of indirect calorimetry, and blood cortisol morning levels were evaluated. Both anorexia nervosa and bulimia nervosa patients showed a reduced REE as compared with predicted REE. Body mass index (BMI) was positively associated with resting energy expenditure in Bulimics, whereas a strong, negative association between BMI and REE was observed in Anorectics. The pattern of associ...Continue Reading

  • References31
  • Citations1


  • References31
  • Citations1


Mentioned in this Paper

Diagnostic and Statistical Manual of Mental Disorders
Energy Metabolism
Body Mass Index Procedure
Mental Disorders
Mediator of activation protein
Entire Hypothalamus
Anorexia Symptom
Adrenal Gland Neoplasms

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