Association between Rosacea and Cardiovascular Diseases and Related Risk Factors: A Systematic Review and Meta-Analysis.

BioMed Research International
Yanmei LiXian Jiang

Abstract

Rosacea is a common inflammatory skin disorder. Several studies, but not all, have suggested a high prevalence of cardiovascular diseases (CVDs) in rosacea patients. This study is aimed at investigating the association between rosacea and CVDs and related risk factors. We performed a literature search through PubMed, Embase, and Web of Science databases, from their respective inception to December 21, 2019. Two reviewers independently screened the articles, extracted data, and performed analysis, following the PRISMA guidelines. Odds ratios (OR) or standardized mean differences (SMD) and 95% confidence intervals (CI) were calculated for outcomes. The included studies' quality was evaluated using the Newcastle Ottawa Scale (NOS). The final meta-analysis included ten studies. The pooled analysis found no association between rosacea prevalence and the incidence of CVDs (OR 0.97; 95% CI 0.86-1.10). Rosacea was found to be significantly associated with several risk factors for CVDs (OR 1.17; 95% CI 1.05-1.31), including hypertension (OR 1.17; 95% CI 1.02-1.35), dyslipidemia (OR 1.34; 95% CI 1.00-1.79), and metabolic syndrome (OR 1.72; 95% CI 1.09-2.72). However, no association was found between rosacea and diabetes mellitus (OR 0.98...Continue Reading

References

Mar 6, 2002·Circulation·Peter LibbyAttilio Maseri
Sep 27, 2005·Lancet·K George M M AlbertiUNKNOWN IDF Epidemiology Task Force Consensus Group
Apr 29, 2006·Arteriosclerosis, Thrombosis, and Vascular Biology·Kristina EdfeldtZhong-qun Yan
Aug 7, 2007·Nature Medicine·Kenshi YamasakiRichard L Gallo
Mar 27, 2013·The Journal of Investigative Dermatology·Eleanor J SamarasekeraCatherine H Smith
May 10, 2013·The Journal of Investigative Dermatology·Julia SpoendlinChristoph R Meier
Jul 23, 2013·Indian Journal of Endocrinology and Metabolism·Sunil K KotaKirtikumar D Modi
Aug 6, 2013·Journal of the European Academy of Dermatology and Venereology : JEADV·N DumanN Atakan
Nov 28, 2013·Journal of the American Academy of Dermatology·Martin SteinhoffJames J Leyden
Jan 17, 2014·The British Journal of Dermatology·J SpoendlinC R Meier
Mar 25, 2014·The Journal of Investigative Dermatology·Jacquelyn R DosalJonette E Keri
Apr 2, 2014·European Heart Journal·Noureddine Idris-KhodjaErnesto L Schiffrin
Jul 23, 2014·Experimental Dermatology·Bodo C Melnik
May 26, 2015·Journal of the American Academy of Dermatology·Tuan-Chun HuaHan-Nan Liu
Aug 11, 2015·Journal of the American Academy of Dermatology·Barbara M RainerAnna L Chien
Jul 23, 2016·Journal of the American Academy of Dermatology·Alexander EgebergJacob P Thyssen
Aug 3, 2016·American Journal of Clinical Dermatology·Alexander EgebergJacob P Thyssen
Aug 23, 2017·Journal of the American Academy of Dermatology·Alexander EgebergNehal N Mehta
Nov 2, 2017·Journal of the American Academy of Dermatology·Anna D HolmesAnne Lynn S Chang
Nov 7, 2017·Journal of the American Academy of Dermatology·Roger Haber, Maria El Gemayel
Feb 27, 2018·The British Journal of Dermatology·L GetherJ P Thyssen
Mar 9, 2019·Acta Dermato-venereologica·Suvi-Päivikki SinikumpuLaura Huilaja
Jun 12, 2019·Journal of the American Academy of Dermatology·Yıldız HayranSibel Ersoy-Evans
Aug 20, 2019·Nature Reviews. Disease Primers·Peter LibbyEldrin F Lewis
Sep 11, 2019·European Heart Journal·François MachUNKNOWN ESC Scientific Document Group
Nov 12, 2019·Journal of the European Academy of Dermatology and Venereology : JEADV·S H LeeJ Shin

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May 19, 2020·Chemical Biology & Drug Design·Ashkan Kalantary-CharvadehMasoud Darabi

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