PMID: 22576377May 12, 2012Paper

Association between silent brain infarct and arterial stiffness indicated by brachial-ankle pulse wave velocity

Internal Medicine
Naoki SajiYasushi Kita

Abstract

The aim of this hospital-based cohort study was to clarify the independent association between silent brain infarct (SBI) and arterial stiffness indicated by brachial-ankle pulse wave velocity (baPWV) including the cutoff value for SBI. We studied 240 consecutive patients (mean age 69 years) with no history of stroke. We assessed the presence of SBI, white matter hyperintensities (WMHs), and risk factors. Arterial stiffness was evaluated using baPWV. We measured the intima-media thickness of the common carotid artery (CCAIMT) using carotid ultrasonography. We divided patients into two groups according to the presence or absence of SBI, and compared clinical characteristics between the two groups. In multivariable analysis, increased baPWV [by 1 m/s; odds ratio (OR) 1.13, 95% confidence interval (CI) 1.02-1.25] was independently associated with SBI. The baPWV cutoff value for SBI was 17.49 m/s. Patients with baPWV≥17.49 m/s had a higher possibility of the presence of SBI (OR 2.30, 95% CI 1.02-5.34) compared with patients with baPWV <17.49 m/s. Furthermore, the adjusted OR for the presence of SBI of the combination of baPWV≥17.49 m/s and CCAIMT≥1.1 mm (OR 2.73, 95% CI 1.24-6.11) was higher compared with that of baPWV≥17.49 m/s (O...Continue Reading

Citations

Feb 20, 2014·Ageing Research Reviews·Joel SingerEvelyn Smith
Dec 17, 2015·Geriatrics & Gerontology International·Naoki SajiTakashi Sakurai
Jan 13, 2015·International Journal of Stroke : Official Journal of the International Stroke Society·Oscar H Del BruttoDavid L Brown
Sep 2, 2015·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Naoki SajiTakashi Sakurai
Apr 23, 2014·Internal Medicine Journal·B LiR-T Wang
Oct 6, 2014·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Kentaro IshizukaShinichiro Uchiyama
Feb 13, 2015·American Journal of Hypertension·Maasa TakahashiMikio Arita
Mar 19, 2015·Journal of the American Medical Directors Association·Ghassan WatfaUNKNOWN PARTAGE study investigators
Apr 2, 2015·Neuroscience and Biobehavioral Reviews·Thomas T van SlotenCoen D A Stehouwer
Feb 27, 2015·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Naoki SajiYasushi Kita
Aug 5, 2016·Alzheimer's & Dementia : Diagnosis, Assessment & Disease Monitoring·Eric McDadeMary Ganguli
Nov 18, 2016·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Naoki SajiTakashi Sakurai
Apr 26, 2014·Journal of Cerebrovascular and Endovascular Neurosurgery·Yeong-Bae LeeHyeon-Mi Park
Sep 6, 2012·Stroke; a Journal of Cerebral Circulation·Naoki SajiYasushi Kita
Mar 2, 2012·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Naoki SajiYasushi Kita
May 28, 2019·Journal of Atherosclerosis and Thrombosis·Xian FuQingchun Gao
Feb 11, 2016·Journal of Atherosclerosis and Thrombosis·Taiki SugimotoRei Ono
Oct 26, 2018·Hypertension·Atsushi TanakaUNKNOWN Physiological Diagnosis Criteria for Vascular Failure Committee

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