Association between systolic blood pressure and uric acid in Chinese children and adolescents with idiopathic short stature: a cross-sectional study.

Journal of Human Hypertension
Shuang KouPing Li

Abstract

The purpose of this study was to investigate the relationship between systolic blood pressure (SBP) and uric acid (UA) in patients with idiopathic short stature (ISS). The present study was a cross-sectional study. A total of 210 Chinese children and adolescents with ISS were included, and their anthropometrics and biochemical parameters were measured. Growth hormone peak levels were assessed after provocation tests with L-dopa and insulin. The univariate analysis results showed a significant positive association between UA and SBP levels (P < 0.001). Furthermore, a non-linear relationship was detected between UA and SBP. In multivariate piecewise linear regression, the inflection point of UA was 4.13 mg/dl (95% CI 3.28, 6.65; P = 0.03), the levels of SBP increased with the increase in UA when the UA level was >4.13 mg/dl (β 2.63, 95% CI: 0.94, 4.31; P = 0.002). However, we did not observe a significant relationship between UA and SBP when the UA level was <4.13 mg/dl (β -2.72, 95% CI -6.89, 1.45; P = 0.202). Our study found a nonlinear relationship between UA and SBP in Chinese children and adolescents with ISS and showed that SBP levels were associated positively with the rise of UA levels when the UA levels reached the infle...Continue Reading

References

Mar 1, 1976·Archives of Disease in Childhood·J M Tanner, R H Whitehouse
Feb 1, 1970·Archives of Disease in Childhood·W A Marshall, J M Tanner
Jun 1, 1969·Archives of Disease in Childhood·W A Marshall, J M Tanner
Aug 6, 2003·Hypertension·Daniel I Feig, Richard J Johnson
Dec 1, 2004·Hypertension·Arnold B AlperL Lee Hamm
Sep 9, 2010·Arthritis Care & Research·Peter C GraysonHyon K Choi
Feb 23, 2013·World Review of Nutrition and Dietetics·Martin O Savage
Apr 9, 2015·The New England Journal of Medicine·Christopher P NelsonUNKNOWN CARDIoGRAM+C4D Consortium
Apr 26, 2017·Journal of Hypertension·Päivi E KorhonenJohan G Eriksson
Dec 27, 2017·Clinica Chimica Acta; International Journal of Clinical Chemistry·Yuan-Yuei ChenWei-Liang Chen
Feb 3, 2018·Medicine·Brianna BourgeoisSteven B Heymsfield

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